2. Anti-infection
  3. Bacterial
  4. Conimine

Conimine 是一种甾体生物碱、抗细菌 (Antibacterial) 剂及增效剂。Conimine 可从 Holarrhena antidysenteriaca Wall.ex A.DC. 种子中分离。Conimine 对甲氧西林敏感型金黄色葡萄球菌 (Staphylococcus aureus) 和耐甲氧西林型 Staphylococcus aureus 具有固有抗菌活性。当与 Penicillin 联用时，Conimine 对耐甲氧西林型金黄色葡萄球菌表现出协同抗菌作用；当与 Vancomycin (HY-B0671) 联用时，其对甲氧西林敏感型和耐甲氧西林型 Staphylococcus aureus 均有协同抗菌作用。

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Conimine

Conimine Chemical Structure

CAS No. : 468-41-7

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Conimine 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Conimine is a steroidal alkaloid, antibacterial agent and potentiator. Conimine is isolated from the seeds of Holarrhena antidysenteriaca Wall.ex A.DC. Conimine exhibits intrinsic antibacterial activity against methicillin-sensitive Staphylococcus aureus and methicillin-resistant Staphylococcus aureus. When combined with Penicillin, Conimine shows synergistic antibacterial effects against methicillin-resistant Staphylococcus aureus; when combined with Vancomycin (HY-B0671), it exerts synergistic antibacterial effects against both methicillin-sensitive and methicillin-resistant Staphylococcus aureus[1].

体外研究
(In Vitro)

Conimine (两倍系列稀释；24 h) 可抑制甲氧西林敏感金黄色葡萄球菌 (MSSA) 和耐甲氧西林金黄色葡萄球菌 (MRSA) 的生长，对两种菌株的 MIC 均为 128 μg·mL−1[1]。
Conimine (1/64-1 of its MIC (128 μg·mL-1)) 对耐甲氧西林金黄色葡萄球菌 (MRSA) 表现出与青霉素协同的抗菌活性，对甲氧西林敏感金黄色葡萄球菌 (MSSA) 和耐甲氧西林金黄色葡萄球菌 (MRSA) 均表现出与万古霉素协同的抗菌活性，而对甲氧西林敏感金黄色葡萄球菌 (MSSA) 与青霉素联用则无相关作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Conimine 相关抗体:
分子量

328.53

Formula

C22H36N2
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Conimine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Conimine468-41-7BacterialHolarrhena antidysenteriacavancomycinmethicillin-sensitive Staphylococcus aureusmethicillin-resistant Staphylococcus aureuspenicillinInhibitorinhibitorinhibit

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