1. Anti-infection
  2. Bacterial Fungal
  3. Dihydroavicine

Dihydroavicine 是一种苯并菲啶类生物碱类抗菌剂,可从 Zanthoxylum rhoifolium 的茎皮中分离得到。Dihydroavicine 可抑制革兰氏阳性菌、革兰氏阴性菌以及白色念珠菌的生长。Dihydroavicine 对酿酒酵母和新型隐球菌无活性。Dihydroavicine 可用于细菌感染、念珠菌感染的研究。

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Dihydroavicine

Dihydroavicine Chemical Structure

CAS No. : 34490-82-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dihydroavicine is a benzophenanthridine alkaloid antibacterial agent isolated from the stem bark of Zanthoxylum rhoifolium. Dihydroavicine inhibits the growth of Gram-positive bacteria, Gram-negative bacteria, and Candida albicans. Dihydroavicine shows no activity against Saccharomyces cerevisiae and Cryptococcus neoformans. Dihydroavicine can be used for the research of bacterial infections and candidal infections[1].

体外研究
(In Vitro)

Dihydroavicine (compound 5) (1.56-12.5 μg; 24-72 h) 可抑制特定革兰氏阳性菌、革兰氏阴性菌以及白色念珠菌 (Candida albicans) 的生长,针对不同微生物的有效抑制剂量范围为 1.56-12.5 μg[1]
Dihydroavicine (100 μg/mL; 24-72 h) 对特定革兰氏阳性菌和革兰氏阴性菌表现出微弱的抑菌活性,MIC 为 100 μg/mL,而对受试酵母无活性[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability AssayWestern Blot AnalysisCell Proliferation AssayApoptosis AnalysisCell Cytotoxicity AssayCell Cycle AnalysisRT-PCRCell Autophagy AssayImmunofluorescenceCell Differentiation AssayCell Invasion AssayCell Migration Assay Real Time qPCRELISA Assay[1]

Cell Line: Gram-positive bacteria, Gram-negative bacteria, and the yeast Candida albicans
Concentration: 1.56-12.5 μg
Incubation Time: 24 h (bacteria); 72 h (yeast)
Result: Exhibited effective inhibitory amounts ranging from 1.56 to 12.5 μg.
分子量

333.34

Formula

C20H15NO4

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Dihydroavicine
目录号:
HY-N18222
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