2. Antibody-drug Conjugate/ADC Related Immunology/Inflammation GPCR/G Protein
  3. Radionuclide-Drug Conjugates (RDCs) CCR
  4. DOTA-ECL1i

DOTA-ECL1i 是 CCR2 抑制剂 ECL1i (HY-P11553) 和 DOTA 偶联物。DOTA-ECL1i 被 68Ga 放射性标记后作为 PET 示踪剂，靶向 CCR2 表达。DOTA-ECL1i 可用于肺纤维化、心脏损伤、腹主动脉瘤炎症、动脉粥样硬化、头颈癌及胰腺癌的相关研究。

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Custom Peptide Synthesis

DOTA-ECL1i

DOTA-ECL1i Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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Customer Review

DOTA-ECL1i 相关抗体

Top Publications Citing Use of Products

查看 Radionuclide-Drug Conjugates (RDCs) 亚型特异性产品:

查看所有亚型
RDC Peptide RDC Antibody RDC Bifunctional Chelator RDC Linker Other

查看 CCR 亚型特异性产品:

查看所有亚型
CCR1 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DOTA-ECL1i is a conjugate of the CCR2 inhibitor ECL1i (HY-P11553) and DOTA. When radiolabeled with 68Ga, DOTA-ECL1i serves as a PET tracer that targets CCR2 expression. DOTA-ECL1i can be used in research related to pulmonary fibrosis, cardiac injury, abdominal aortic aneurysm inflammation, atherosclerosis, head and neck cancer, and pancreatic cancer[1].

IC50 & Target[1]

CCR2

 

分子量

1307.51

Formula

C58H94N14O18S
Sequence

d(Leu-Gly-Thr-Phe-Leu-Lys-Cys)-Mal-DOTA
Sequence Shortening

d(LGTFLKC)-Mal-DOTA
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DOTA-ECL1i 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DOTA-ECL1iRadionuclide-Drug Conjugates (RDCs)CCRCC chemokine receptorpancreatic cancerCCR2atherosclerosisgallium-68juxtamembranous extracellular loop 1PET tracerheart injuryhead and neck cancerabdominal aortic aneurysm inflammationpulmonary fibrosisInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-P11553B
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