2. Others Cytoskeleton Apoptosis
  3. Reference Standards Dynamin Apoptosis
  4. Dynole 34-2 (Standard)

Dynole 34-2 (Standard) 是 Dynole 34-2 (HY-107545) 的分析标准品。本产品用于研究及分析应用。Dynole 34-2 是一种有效的 dynamin GTPase 抑制剂 (对 dynamin 1 和 dynamin 2 GTPase 活性的 IC50s 值分别为 6.9 和 14.2 µM)，具有抗有丝分裂的作用。Dynole 34-2 诱导细胞凋亡 (apoptosis)，如细胞空泡、DNA 断裂和 PARP 剪切。Dynole 34-2 也能有效抑制受体介导的内吞作用 (RME)。

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Dynole 34-2 (Standard)

Dynole 34-2 (Standard) Chemical Structure

CAS No. : 1128165-88-7

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生物活性

Dynole 34-2 (Standard) is the analytical standard of Dynole 34-2 (HY-107545). This product is intended for research and analytical applications. Dynole 34-2 is a potent dynamin GTPase inhibitor (IC50s=6.9 and 14.2 µM for dynamin1 and dynamin2 GTPase activity, respectively) with antimitotic effect. Dynole 34-2 induces apoptosis, as revealed by cell blebbing, DNA fragmentation, and PARP cleavage. Dynole 34-2 also potently inhibits receptor mediated endocytosis (RME)[1][2].

分子量

408.58

Formula

C25H36N4O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Dynole 34-2 (Standard) 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Dynole 34-2 (Standard)1128165-88-7Reference StandardsDynaminApoptosisInhibitorinhibitorinhibit

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