2. Gene
  3. Gsr - glutathione-disulfide reductase Gene

Gsr - glutathione-disulfide reductase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 116686 | 基因类型: protein coding

关于 Gsr

功能概要

Enables several functions, including glutathione binding activity; glutathione-disulfide reductase (NADPH) activity; and nucleotide binding activity. Involved in several processes, including response to iron(III) ion; response to ischemia; and response to vitamin A. Located in cytosol and mitochondrion. Used to study cataract and transient cerebral ischemia. Biomarker of several diseases, including Parkinsonism; acute kidney failure (multiple); hemorrhagic cystitis; myoglobinuria; and neurodegenerative disease (multiple). Human ortholog(s) of this gene implicated in macular degeneration. Orthologous to human GSR (glutathione-disulfide reductase). [provided by Alliance of Genome Resources, Apr 2022]

Gsr 基因产物(1)

mRNA Protein Name
NM_053906.2 NP_446358.2 glutathione reductase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables NADP binding IDA
IDA: 通过直接分析推断
237922 RGD
enables flavin adenine dinucleotide binding IDA
IDA: 通过直接分析推断
237922 RGD
enables glutathione binding IDA
IDA: 通过直接分析推断
237922 RGD
enables glutathione-disulfide reductase (NADPH) activity IDA
IDA: 通过直接分析推断
237922 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
237922 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in glutathione metabolic process IDA
IDA: 通过直接分析推断
237922 RGD
involved in response to activity IEP
IEP: 通过表达模式推断
21621560 RGD
involved in response to cadmium ion IEP
IEP: 通过表达模式推断
24758558 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
23905773 RGD
involved in response to iron(III) ion IEP
IEP: 通过表达模式推断
24388910 RGD
involved in response to ischemia IEP
IEP: 通过表达模式推断
9434704 RGD
involved in response to nicotine IEP
IEP: 通过表达模式推断
22894698 RGD
involved in response to oxidative stress IEP
IEP: 通过表达模式推断
21704983 RGD
involved in response to vitamin A IEP
IEP: 通过表达模式推断
22984325 RGD
involved in spermatogenesis IMP
IMP: 通过突变表型推断
11874473 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

glutathione reductase

GR

GRase

glutathione reductase, mitochondrial

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-147328 LCS3 Inducer 99.43% 否
HY-RS05870 GSR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18327 Gsr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24806 Gsr Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gsr NCBI NCBI:2936
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