1. Gene
  2. Gabra4 - gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4 Gene

Gabra4 - gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4 Gene

种属: Mus musculus

同用名: Gabra-4

基因 ID: 14397 | 基因类型: protein coding

关于 Gabra4

功能概要

Predicted to enable GABA-gated chloride ion channel activity; inhibitory extracellular ligand-gated ion channel activity; and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to contribute to GABA-A receptor activity; benzodiazepine receptor activity; and Chloride Channel activity. Acts upstream of or within central nervous system development. Predicted to be located in postsynaptic membrane. Predicted to be integral component of membrane. Predicted to be part of GABA-A receptor complex. Predicted to be active in dendrite membrane and postsynapse. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and spinal cord. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human GABRA4 (gamma-aminobutyric acid type A receptor subunit alpha4). [provided by Alliance of Genome Resources, Apr 2022]

Gabra4 基因产物(9)

mRNA Protein Name
NM_001359041.1 NP_001345970.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 1 precursor
NM_001359043.1 NP_001345972.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 3
NM_001359044.1 NP_001345973.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 4 precursor
NM_001359045.1 NP_001345974.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 5 precursor
NM_001359046.1 NP_001345975.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 6 precursor
NM_001359047.1 NP_001345976.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 7 precursor
NM_001359048.1 NP_001345977.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 8 precursor
NM_001359050.1 NP_001345979.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 9 precursor
NM_010251.2 NP_034381.1 gamma-aminobutyric acid receptor subunit alpha-4 isoform 2 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within central nervous system development IMP
IMP: 通过突变表型推断
17005728 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

gamma-aminobutyric acid receptor subunit alpha-4

GABA(A) receptor subunit alpha-4

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gabra4 NCBI NCBI:2557