1. Gene
  2. Gpld1 - glycosylphosphatidylinositol specific phospholipase D1 Gene

Gpld1 - glycosylphosphatidylinositol specific phospholipase D1 Gene

种属: Mus musculus

同用名: 6330541J12Rik

基因 ID: 14756 | 基因类型: protein coding

关于 Gpld1

功能概要

Enables glycosylphosphatidylinositol Phospholipase D activity and Sodium Channel regulator activity. Involved in several processes, including positive regulation of high-density lipoprotein particle clearance; positive regulation of Insulin secretion involved in cellular response to glucose stimulus; and regulation of triglyceride metabolic process. Acts upstream of or within GPI anchor release; chondrocyte differentiation; and ossification. Located in several cellular components, including extracellular matrix; extracellular space; and intracellular membrane-bounded organelle. Is expressed in several structures, including alimentary system; central nervous system; ear; genitourinary system; and skeleton. Orthologous to human GPLD1 (glycosylphosphatidylinositol specific Phospholipase D1). [provided by Alliance of Genome Resources, Apr 2022]

Gpld1 基因产物(1)

mRNA Protein Name
NM_008156.2 NP_032182.2 phosphatidylinositol-glycan-specific phospholipase D precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables glycosylphosphatidylinositol phospholipase D activity IDA
IDA: 通过直接分析推断
1833386 MGI
enables phospholipase D activity IDA
IDA: 通过直接分析推断
9716655 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
23055941 MGI
enables sodium channel regulator activity IMP
IMP: 通过突变表型推断
16822939 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15946906 MGI
located in extracellular matrix IDA
IDA: 通过直接分析推断
15946906 MGI
located in extracellular region IDA
IDA: 通过直接分析推断
1833386 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
16219662 MGI
located in intracellular membrane-bounded organelle IDA
IDA: 通过直接分析推断
1833386 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

phosphatidylinositol-glycan-specific phospholipase D

GPI-PLD

GPI-specific phospholipase D

PI-G PLD

glycoprotein phospholipase D

glycosyl-phosphatidylinositol-specific phospholipase D

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gpld1 NCBI NCBI:2822