2. Gene
  3. Jup - junction plakoglobin Gene

Jup - junction plakoglobin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: PG; Ctnng; D930025P04Rik

基因 ID: 16480 | 基因类型: protein coding

关于 Jup

功能概要

Enables alpha-catenin binding activity. Acts upstream of or within cell-cell adhesion; desmosome assembly; and skin development. Located in several cellular components, including Z disc; adherens junction; and intermediate filament. Part of catenin complex. Is expressed in several structures, including alimentary system; musculature; nervous system; reproductive system; and sensory organ. Used to study arrhythmogenic right ventricular dysplasia 12 and epidermolytic hyperkeratosis. Human ortholog(s) of this gene implicated in cardiomyopathy (multiple); palmoplantar keratosis (multiple); renal cell carcinoma; and reproductive organ Cancer (multiple). Orthologous to human JUP (junction plakoglobin). [provided by Alliance of Genome Resources, Apr 2022]

Jup 基因产物(1)

mRNA Protein Name
NM_010593.2 NP_034723.1 junction plakoglobin
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables alpha-catenin binding IPI
IPI: 通过物理相互作用推断
14579029 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12847106 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell adhesion IDA
IDA: 通过直接分析推断
12847106 MGI
acts upstream of or within cell-cell adhesion IMP
IMP: 通过突变表型推断
8954745 MGI
acts upstream of or within desmosome assembly IMP
IMP: 通过突变表型推断
8954745 MGI
acts upstream of or within skin development IMP
IMP: 通过突变表型推断
8954745 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Z disc IDA
IDA: 通过直接分析推断
8821035 MGI
located in adherens junction IDA
IDA: 通过直接分析推断
8582267 MGI
part of catenin complex IDA
IDA: 通过直接分析推断
8853988 MGI
located in cell-cell junction IDA
IDA: 通过直接分析推断
12847106 MGI
is active in cornified envelope IDA
IDA: 通过直接分析推断
26644517 MGI
located in cytosol IDA
IDA: 通过直接分析推断
12847106 MGI
located in desmosome IDA
IDA: 通过直接分析推断
9864371 MGI
located in desmosome IMP
IMP: 通过突变表型推断
18496566 MGI
located in intermediate filament IDA
IDA: 通过直接分析推断
16917092 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

junction plakoglobin

desmoplakin III

desmoplakin-3

gamma-catenin

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07061 JUP Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18118 Jup Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24592 Jup Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Jup NCBI NCBI:3728
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z