2. Gene
  3. Smad6 - SMAD family member 6 Gene

Smad6 - SMAD family member 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Madh6; b2b390Clo

基因 ID: 17130 | 基因类型: protein coding

关于 Smad6

功能概要

Predicted to enable several functions, including SMAD binding activity; signaling receptor binding activity; and transcription regulator inhibitor activity. Involved in heart development; negative regulation of ossification; and positive regulation of pri-miRNA transcription by RNA polymerase II. Acts upstream of or within circulatory system development and ureteric bud development. Predicted to be located in Golgi apparatus; cytosol; and nuclear body. Predicted to be part of heteromeric SMAD protein complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in aortic valve disease 2; craniosynostosis; and radioulnar synostosis. Orthologous to human SMAD6 (Smad Family member 6). [provided by Alliance of Genome Resources, Apr 2022]

Smad6 基因产物(1)

mRNA Protein Name
NM_008542.3 NP_032568.3 mothers against decapentaplegic homolog 6
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16601693 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within aorta development IMP
IMP: 通过突变表型推断
25807483 MGI
acts upstream of or within coronary vasculature development IMP
IMP: 通过突变表型推断
25807483 MGI
acts upstream of or within heart valve development IMP
IMP: 通过突变表型推断
25807483 MGI
involved in mitral valve morphogenesis IMP
IMP: 通过突变表型推断
10655064 MGI
involved in negative regulation of ossification IMP
IMP: 通过突变表型推断
10655064 MGI
involved in outflow tract septum morphogenesis IMP
IMP: 通过突变表型推断
10655064 MGI
involved in positive regulation of miRNA transcription IMP
IMP: 通过突变表型推断
21145505 MGI
involved in pulmonary valve morphogenesis IMP
IMP: 通过突变表型推断
10655064 MGI
involved in ureteric bud development IEP
IEP: 通过表达模式推断
14656760 MGI
acts upstream of or within ventricular septum development IMP
IMP: 通过突变表型推断
25807483 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

mothers against decapentaplegic homolog 6

MAD homolog 6

Smad 6

mad homolog 7

mothers against DPP homolog 6

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13397 SMAD6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18407 Smad6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24888 Smad6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Smad6 NCBI NCBI:4091
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z