ADAM32 - ADAM metallopeptidase domain 32 Gene

中文名称：ADAM 金属肽酶结构域 32

种属: Homo sapiens

关于 ADAM32

功能概要

该基因编码膜锚定蛋白解联蛋白家族的一个成员，该蛋白在大脑发育、受精、肿瘤发展和炎症等多种生物过程中发挥作用。该基因主要在睾丸中表达。编码的蛋白质经过蛋白水解加工，生成由金属蛋白酶、解联蛋白和表皮生长因子样结构域组成的成熟多肽。该基因位于 8 号染色体上的其他解整合素和金属肽酶家族基因簇中。可变剪接导致编码不同亚型的多个转录变体。[RefSeq 提供，2015 年 9 月]

This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. This gene is predominantly expressed in the testis. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene is located in a cluster of Other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]