2. Gene
  3. VCAM1 - Vcam1 vascular cell adhesion molecule 1 Gene

VCAM1 - Vcam1 vascular cell adhesion molecule 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: VCAM1B

基因 ID: 25361 | 基因类型: protein coding

关于 VCAM1

功能概要

Enables Integrin binding activity. Involved in several processes, including cellular response to tumor necrosis factor; nervous system development; and response to lipopolysaccharide. Located in cell surface; extracellular space; and sarcolemma. Used to study carotid stenosis and hypertension. Biomarker of several diseases, including artery disease (multiple); chronic kidney disease; colitis; periodontitis; and thromboangiitis obliterans. Orthologous to human VCAM1 (vascular cell adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

VCAM1 基因产物(2)

mRNA Protein Name
NM_012889.2 NP_037021.1 vascular cell adhesion protein 1 precursor
NM_012889.2 NP_037021.1 vascular cell adhesion protein 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables integrin binding IMP
IMP: 通过突变表型推断
1377031 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cardiac neuron differentiation IMP
IMP: 通过突变表型推断
12486170 RGD
involved in cell adhesion IMP
IMP: 通过突变表型推断
1377031 RGD
involved in cell chemotaxis IMP
IMP: 通过突变表型推断
23226762 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: 通过表达模式推断
15980038 RGD
involved in cellular response to vascular endothelial growth factor stimulus IEP
IEP: 通过表达模式推断
23226762 RGD
involved in chronic inflammatory response IEP
IEP: 通过表达模式推断
10706728 RGD
involved in innervation IMP
IMP: 通过突变表型推断
12486170 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
22521742 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
19465514 RGD
involved in response to ionizing radiation IEP
IEP: 通过表达模式推断
19714308 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
22433071 RGD
involved in response to nicotine IEP
IEP: 通过表达模式推断
22218593 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
19199090 RGD
involved in response to zinc ion IEP
IEP: 通过表达模式推断
20128680 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
11870719 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
22521742 RGD
located in sarcolemma IDA
IDA: 通过直接分析推断
11870719 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

vascular cell adhesion protein 1

V-CAM 1

VCAM-1

vascular cell adhesion protein 1-like

相关产品

Approval
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-108831 Natalizumab Inhibitor 99.10% 否
Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-167874 ASP-8731 Inhibitor 98.42% Phase 1
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-108831A Natalizumab (Solution) Inhibitor ≥99.0% Phase 4
Pre-clinical Phase
生物活性分子 (26)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-112868B ABH hydrochloride 99.90% 否
HY-N0602 Ginsenoside Rg2 Inhibitor 98.11% 否
HY-121705 Propionyl-L-carnitine 95.0% 否
HY-N2110 Phellopterin 99.94% 否
HY-N1353 Rhamnocitrin Inhibitor 99.67% 否
HY-N7688 Regaloside B Inhibitor 99.90% 否
HY-N0617 Sanggenon C 98.46% 否
HY-139702 α5β1 integrin agonist-1 99.67% 否
HY-W588250 Surfactin C1 Antagonist 99.36% 否
HY-14921 Elsibucol Inhibitor 99.35% 否
HY-P11445 GREDVGC / 否
HY-RS17114 Vcam1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-119142 CP-664511 Antagonist / 否
HY-143243 Antioxidant agent-5 Inhibitor / 否
HY-159179 α4 integrin receptor antagonist 3 Inhibitor / 否
HY-163712S 17-Epiestriol-d5-1 / 否
HY-170916 Angiogenesis inhibitor 7 Inhibitor / 否
HY-171216 GW559090 Antagonist / 否
HY-180385 Desferricoprogen Inhibitor / 否
HY-N0602R Ginsenoside Rg2 (Standard) Inhibitor / 否
HY-N10047 7,8-Didehydrocimigenol Inhibitor / 否
HY-P11088 VCAM1 binding peptide Ligand / 否
HY-RS15618 VCAM1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-127113 Q8 Antagonist / 否
HY-163712 17-Epiestriol Agonist / 否
HY-RS23559 Vcam1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990294 Anti-Mouse CD106/VCAM-1 Antibody (M/K-2.7) Inhibitor 95.00% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens VCAM1 NCBI NCBI:7412
Macaca fascicularis VCAM1 NCBI NCBI:102131307
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