Tinf2 - TERF1 interacting nuclear factor 2 Gene

种属: Rattus norvegicus

关于 Tinf2

功能概要

Predicted to enable telomeric DNA binding activity. Predicted to be involved in several processes, including negative regulation of nitrogen compound metabolic process; protein localization to chromosome, telomeric region; and telomere organization. Predicted to act upstream of or within negative regulation of telomere maintenance. Predicted to be located in chromosome, telomeric region; nuclear body; and perinucleolar chromocenter. Predicted to be part of shelterin complex. Human ortholog(s) of this gene implicated in Revesz syndrome and autosomal dominant dyskeratosis congenita 3. Orthologous to human TINF2 (TERF1 interacting nuclear factor 2). [provided by Alliance of Genome Resources, Apr 2022]