GSTT2 - glutathione S-transferase theta 2 (gene/pseudogene) Gene

中文名称：谷胱甘肽 S-转移酶 theta 2 (基因/假基因)

种属: Homo sapiens

关于 GSTT2

功能概要

由该基因编码的蛋白质谷胱甘肽 S-转移酶 (GST) theta 2 (GSTT2) 是蛋白质超家族的成员，可催化还原型谷胱甘肽与各种亲电子和疏水化合物的结合。人类 GST 可分为五个主要类别：alpha、mu、pi、theta 和 zeta。 theta 类包括 GSTT1、GSTT2 和 GSTT2B。 GSTT2 和 GSTT2B 彼此几乎相同，与 GSTT1 具有 55% 的氨基酸同一性。这三个基因都可能在人类致癌过程中发挥作用。 GSTT2 基因在某些人群中是假基因。[RefSeq 提供，2015 年 9 月]

The protein encoded by this gene, Glutathione S-transferase (GST) theta 2 (GSTT2), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT2 and GSTT2B are nearly identical to each Other, and share 55% amino acid identity with GSTT1. All three genes may play a role in human carcinogenesis. The GSTT2 gene is a pseudogene in some populations. [provided by RefSeq, Sep 2015]