1. Gene
  2. Mad2l2 - mitotic arrest deficient 2 like 2 Gene

Mad2l2 - mitotic arrest deficient 2 like 2 Gene

种属: Rattus norvegicus

基因 ID: 313702 | 基因类型: protein coding

关于 Mad2l2

功能概要

Predicted to enable JUN kinase binding activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Predicted to be involved in several processes, including negative regulation of cell-cell adhesion mediated by cadherin; regulation of nucleobase-containing compound metabolic process; and regulation of protein metabolic process. Predicted to be located in cytosol; nucleolus; and spindle. Predicted to be part of zeta DNA Polymerase complex. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group V. Orthologous to human MAD2L2 (mitotic arrest deficient 2 like 2). [provided by Alliance of Genome Resources, Apr 2022]

Mad2l2 基因产物(2)

mRNA Protein Name
NM_001012106.2 NP_001012106.1 mitotic spindle assembly checkpoint protein MAD2B isoform 2
NM_001394241.1 NP_001381170.1 mitotic spindle assembly checkpoint protein MAD2B isoform 1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of epithelial to mesenchymal transition IMP
IMP: 通过突变表型推断
27488450 RGD
involved in positive regulation of extracellular matrix assembly IMP
IMP: 通过突变表型推断
27488450 RGD
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
27488450 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

mitotic spindle assembly checkpoint protein MAD2B

MAD2 mitotic arrest deficient-like 2

MAD2-like protein 2

mitotic arrest deficient 2-like protein 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mad2l2 NCBI NCBI:10459