1. Gene
  2. Dnmt3b - DNA methyltransferase 3 beta Gene

Dnmt3b - DNA methyltransferase 3 beta Gene

种属: Rattus norvegicus

基因 ID: 444985 | 基因类型: protein coding

关于 Dnmt3b

功能概要

Enables DNA binding activity; chromatin binding activity; and histone deacetylase binding activity. Involved in several processes, including cellular response to dexamethasone stimulus; cellular response to hyperoxia; and response to alkaloid. Located in cytoplasm and nucleus. Biomarker of anxiety disorder; congenital heart disease; hepatocellular carcinoma; and prostatitis. Human ortholog(s) of this gene implicated in several diseases, including acute myeloid leukemia; autoimmune disease (multiple); carcinoma (multiple); immunodeficiency-centromeric instability-facial anomalies syndrome 1; and thymoma. Orthologous to human DNMT3B (DNA Methyltransferase 3 beta). [provided by Alliance of Genome Resources, Apr 2022]

Dnmt3b 基因产物(1)

mRNA Protein Name
NM_001396349.1 NP_001383278.1 DNA (cytosine-5)-methyltransferase 3B
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
23671328 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
23671328 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to dexamethasone stimulus IEP
IEP: 通过表达模式推断
23671328 RGD
involved in cellular response to hyperoxia IEP
IEP: 通过表达模式推断
23039253 RGD
involved in response to activity IEP
IEP: 通过表达模式推断
23201423 RGD
involved in response to alcohol IEP
IEP: 通过表达模式推断
26509893 RGD
involved in response to caffeine IEP
IEP: 通过表达模式推断
24717552 RGD
involved in response to cocaine IEP
IEP: 通过表达模式推断
23688924 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
22334722 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
23529784 RGD
involved in response to ionizing radiation IEP
IEP: 通过表达模式推断
17148264 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
23433207 RGD
involved in response to vitamin A IEP
IEP: 通过表达模式推断
23333085 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
16632870 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

DNA (cytosine-5)-methyltransferase 3B

DNA (cytosine-5-)-methyltransferase 3 beta

DNA methyltransferase 3B

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dnmt3b NCBI NCBI:1789