2. Gene
  3. Egln3 - egl-9 family hypoxia-inducible factor 3 Gene

Egln3 - egl-9 family hypoxia-inducible factor 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: PHD3; PHD-3; SM-20

基因 ID: 54702 | 基因类型: protein coding

关于 Egln3

功能概要

Predicted to enable ferrous iron binding activity and peptidyl-proline 4-dioxygenase activity. Involved in regulation of cell population proliferation. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Biomarker of acute kidney failure and myocardial infarction. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human EGLN3 (egl-9 family hypoxia inducible factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Egln3 基因产物(1)

mRNA Protein Name
NM_019371.2 NP_062244.2 prolyl hydroxylase EGLN3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20849813 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of cell population proliferation IMP
IMP: 通过突变表型推断
12379765 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

prolyl hydroxylase EGLN3

HIF-PH3

HIF-prolyl hydroxylase 3

HPH-3

egl nine homolog 3, mitochondrial

factor-responsive smooth muscle protein

hypoxia-inducible factor prolyl hydroxylase 3

prolyl hydroxylase domain-containing protein 3

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-168533 ZG-2305 Inhibitor 98.60% 否
HY-RS04214 EGLN3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20396 Egln3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26905 Egln3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Egln3 NCBI NCBI:112399
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