2. Gene
  3. PIGX - phosphatidylinositol glycan anchor biosynthesis class X Gene

PIGX - phosphatidylinositol glycan anchor biosynthesis class X Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：磷脂酰肌醇聚糖锚生物合成 X 类

种属: Homo sapiens

同用名: PIG-X

基因 ID: 54965 | 基因类型: protein coding

关于 PIGX

Cytogenetic location: 3q29 Genomic coordinates (GRCh38): 3:196,712,377-196,736,007 (from NCBI)

This gene has 9 transcripts (splice variants) and 192 orthologues. Ubiquitous expression in brain (RPKM 7.7), prostate (RPKM 7.3) and 25 other tissues.

功能概要

该基因在内质网 (ER) 中编码 I 型跨膜蛋白。该蛋白质是糖基磷脂酰肌醇-甘露糖基转移酶 I 的重要组成部分，它在 GPI 锚生物合成过程中转移 GPI 锚前体中四种甘露糖中的第一个。大鼠研究表明该蛋白质是从非 AUG 翻译起始位点翻译而来的。可变剪接导致多个转录本变体。[RefSeq 提供，2009 年 10 月]

This gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER). The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Studies in rat indicate that the protein is translated from a non-AUG translation initiation site. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

PIGX 基因产物(2)

mRNA Protein Name
NM_001166304.2 NP_001159776.1 phosphatidylinositol-glycan biosynthesis class X protein isoform 1 precursor
NM_017861.4 NP_060331.3 phosphatidylinositol-glycan biosynthesis class X protein isoform 2 precursor

PIGX 蛋白结构

PIG-X

PIG-X: PIG-X / PBN1 (54 - 252)

  • 0
  • 100
  • 200
  • 258 a.a.
蛋白主名 其他名称

phosphatidylinositol-glycan biosynthesis class X protein

GPI-mannosyltransferase subunit

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10506 PIGX Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PIGX RGD RGD:1307289
Macaca mulatta PIGX VGNC VGNC:75867
Canis familiaris PIGX VGNC VGNC:44546
Felis catus PIGX VGNC VGNC:64172
Mus musculus PIGX MGD MGI:1919334
Bos taurus PIGX VGNC VGNC:53598
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