2. Gene
  3. Akr1a1 - aldo-keto reductase family 1, member A1 (aldehyde reductase) Gene

Akr1a1 - aldo-keto reductase family 1, member A1 (aldehyde reductase) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Akr1a4; 2610201A18Rik

基因 ID: 58810 | 基因类型: protein coding

关于 Akr1a1

功能概要

Enables L-glucuronate reductase activity; alditol:NADP+ 1-oxidoreductase activity; and glucuronolactone reductase activity. Involved in cellular detoxification of aldehyde. Acts upstream of or within D-glucuronate catabolic process; L-ascorbic acid biosynthetic process; and aldehyde catabolic process. Located in apical plasma membrane and cytosol. Is active in synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human AKR1A1 (aldo-keto reductase family 1 member A1). [provided by Alliance of Genome Resources, Apr 2022]

Akr1a1 基因产物(1)

mRNA Protein Name
NM_021473.3 NP_067448.1 aldo-keto reductase family 1 member A1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables L-glucuronate reductase activity IDA
IDA: 通过直接分析推断
15769935 MGI
enables L-glucuronate reductase activity IMP
IMP: 通过突变表型推断
20410296 MGI
enables S-nitrosoglutathione reductase (NADH) activity IMP
IMP: 通过突变表型推断
31649033 MGI
enables aldose reductase (NADPH) activity IDA
IDA: 通过直接分析推断
14667815 MGI
enables glucuronolactone reductase activity IDA
IDA: 通过直接分析推断
22820017 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within D-glucuronate catabolic process IDA
IDA: 通过直接分析推断
15769935 MGI
involved in D-glucuronate catabolic process to D-xylulose 5-phosphate IDA
IDA: 通过直接分析推断
38160 MGI
acts upstream of or within L-ascorbic acid biosynthetic process IDA
IDA: 通过直接分析推断
15769935 MGI
involved in L-ascorbic acid biosynthetic process IMP
IMP: 通过突变表型推断
20410296 MGI
acts upstream of or within aldehyde catabolic process IDA
IDA: 通过直接分析推断
15769935 MGI
involved in cellular detoxification of aldehyde IMP
IMP: 通过突变表型推断
22820017 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
15769935 MGI
is active in cytosol IDA
IDA: 通过直接分析推断
38160 MGI
located in cytosol IDA
IDA: 通过直接分析推断
15769935 MGI
is active in synapse EXP
EXP: 通过实验结果推断
16635246 MGI
is active in synapse IDA
IDA: 通过直接分析推断
16635246 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

aldo-keto reductase family 1 member A1

alcohol dehydrogenase

aldehyde reductase

aldo-keto reductase family 1, member A4 (aldehyde reductase)

glucuronate reductase

glucuronolactone reductase

相关产品

Pre-clinical Phase
生物活性分子 (39)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N0376 Liquiritin 99.99% 否
HY-150644 S07-2010 Inhibitor 98.35% 否
HY-106697 Ponalrestat Inhibitor 99.51% 否
HY-114009 AKR1C1-IN-1 Inhibitor 99.38% 否
HY-133708 β-Glucogallin 99.82% 否
HY-113114 Tetrahydrocortisone Substrate 99.96% 否
HY-D1341 Coumberone 99.73% 否
HY-N0310 Soyasaponin Bb 99.88% 否
HY-N2282 Zingiberen newsaponin 99.68% 否
HY-N8549A 5-Dihydrocortisone 99.83% 否
HY-N0412 Sesamoside Inhibitor 99.77% 否
HY-RS00532 AKR1B1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-118819 5-Bromo-3-phenyl salicylic acid Inhibitor 98.00% 否
HY-RS17235 Akr1b1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-W069545 (S)-1-Tetralol 99.75% 否
HY-113850 CPSA Inhibitor / 否
HY-131586 3,7-Dihydroxyflavone 98.04% 否
HY-149254 PTP1B/AKR1B1-IN-1 Inhibitor / 否
HY-149255 PTP1B/AKR1B1-IN-2 Inhibitor / 否
HY-156701 BAY-1128688 Inhibitor / 否
HY-163609 PROTAC AKR1C3 degrader-1 Degrader / 否
HY-172598 Keap1-Nrf2-IN-28 Inhibitor / 否
HY-173132 AKR1Cs-IN-1 Inhibitor / 否
HY-175331 ALR2-IN-7 Inhibitor 99.94% 否
HY-175639 ALR2-IN-8 Inhibitor / 否
HY-176719 AKR1B1/STAT3/SLC7A11-regulator-1 / 否
HY-177415 JSD26 Inhibitor / 否
HY-181542 SG-55 Inhibitor / 否
HY-N0376R Liquiritin (Standard) / 否
HY-RS00531 AKR1A1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS00534 AKR1C1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS00538 AKR1D1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-124432 CRT0093964 Inhibitor / 否
HY-RS17921 Akr1a1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18415 Akr1d1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23471 Akr1c1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23688 Akr1b1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24390 Akr1a1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24896 Akr1d1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Akr1a1 NCBI NCBI:10327
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