2. Gene
  3. ADGRL4 - adhesion G protein-coupled receptor L4 Gene

ADGRL4 - adhesion G protein-coupled receptor L4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：粘附 G 蛋白偶联受体 L4

种属: Homo sapiens

同用名: ETL; ELTD1; KPG_003

基因 ID: 64123 | 基因类型: protein coding

关于 ADGRL4

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:78,889,764-79,006,730 (from NCBI)

This gene has 17 transcripts (splice variants), 198 orthologues and 42 paralogues. Broad expression in fat (RPKM 38.7), spleen (RPKM 20.4) and 20 other tissues.

功能概要

预计可启用 G 蛋白偶联受体活性。预计参与腺苷酸环化酶激活 G 蛋白偶联受体信号通路。预测位于细胞质囊泡和质膜。预计是质膜的组成部分。胶质母细胞瘤和肥厚性心肌病的生物标志物。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in cytoplasmic vesicle and plasma membrane. Predicted to be integral component of plasma membrane. Biomarker of glioblastoma and hypertrophic cardiomyopathy. [provided by Alliance of Genome Resources, Apr 2022]

ADGRL4 基因产物(1)

mRNA Protein Name
NM_022159.4 NP_071442.2 adhesion G protein-coupled receptor L4 precursor

ADGRL4 蛋白结构

EGF_CA

EGF_CA: Calcium-binding EGF domain (58 - 94)

(131 - 343)

GPS

GPS: GPCR proteolysis site, GPS, motif (368 - 413)

7tm_2

7tm_2: 7 transmembrane receptor (Secretin family) (427 - 660)

  • 0
  • 200
  • 400
  • 600
  • 690 a.a.
蛋白主名 其他名称

adhesion G protein-coupled receptor L4

EGF, latrophilin and seven transmembrane domain containing 1

关联疾病

疾病名称 别名
Transient Refractive Change
Volkmann Contracture

Ischemic Contracture

Volkmann'S Ischemic Contracture
Usher Syndrome, Type Iic

Usher Syndrome Type 2c

USH2C

Usher Syndrome, Type 2c

Usher Syndrome, Type Iic, Gpr98/Pdzd7 Digenic

Usher Syndrome Type Iic

Usher Syndrome, Type 2c, Gpr98/Pdzd7 Digenic

Usher Syndrome 2c

Usher'S Syndrome Type 2c

Usher Syndrome Type Iic Gpr98/Pdzd7 Digenic
Idh-Wildtype Anaplastic Astrocytoma
Tympanosclerosis

Ts - [Tympanosclerosis]

Tympanic Membrane Sclerosis
Tympanic Membrane Disease

Disorder Of Tympanic Membrane
Glioblastoma

Glioblastoma Multiforme

Gbm

Adult Glioblastoma Multiforme

Grade Iv Adult Astrocytic Tumor

Primary Glioblastoma Multiforme

Spongioblastoma Multiforme

Adult Glioblastoma

Primary Glioblastoma
Hypertrophic Cardiomyopathy

Hypertrophic Obstructive Cardiomyopathy

Cardiomyopathy, Hypertrophic

Cardiomyopathy Hypertrophic Obstructive

Cardiomyopathy, Hypertrophic, Familial

Idiopathic Myocardial Hypertrophy

Idiopathic Hypertrophic Cardiomyopathy

Obstructive Idiopathic Hypertrophic Cardiomyopathy

Obstructive Cardiomyopathy

Idiopathic Hypertrophic Subaortic Stenosis

Muscular Subaortic Stenosis

Hypertrophic Obstructive Subaortic Stenosis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00364 ADGRL4 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus ADGRL4 MGD MGI:2655562
Rattus norvegicus ADGRL4 RGD RGD:621136
Macaca mulatta ADGRL4 VGNC VGNC:69652
Canis familiaris ADGRL4 VGNC VGNC:37653
Felis catus ADGRL4 VGNC VGNC:59640
Bos taurus ADGRL4 VGNC VGNC:25672
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