2. Gene
  3. Izumo1 - izumo sperm-egg fusion 1 Gene

Izumo1 - izumo sperm-egg fusion 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Izumo; 1700058F15Rik

基因 ID: 73456 | 基因类型: protein coding

关于 Izumo1

功能概要

Enables protein binding activity involved in heterotypic cell-cell adhesion; protein homodimerization activity; and signaling receptor binding activity. Involved in fusion of sperm to egg plasma membrane involved in single fertilization; heterotypic cell-cell adhesion; and sperm-egg recognition. Located in acrosomal membrane and plasma membrane. Is integral component of membrane. Orthologous to human IZUMO1 (izumo sperm-egg fusion 1). [provided by Alliance of Genome Resources, Apr 2022]

Izumo1 基因产物(1)

mRNA Protein Name
NM_001018013.1 NP_001018013.1 izumo sperm-egg fusion protein 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20421979 MGI
enables protein binding involved in heterotypic cell-cell adhesion IDA
IDA: 通过直接分析推断
35960805 MGI
enables protein binding involved in heterotypic cell-cell adhesion IMP
IMP: 通过突变表型推断
27309808 MGI
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
19658160 MGI
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
24739963 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in fusion of sperm to egg plasma membrane involved in single fertilization IDA
IDA: 通过直接分析推断
15759005 MGI
involved in fusion of sperm to egg plasma membrane involved in single fertilization IMP
IMP: 通过突变表型推断
24739963 MGI
involved in heterotypic cell-cell adhesion IMP
IMP: 通过突变表型推断
27309808 MGI
involved in single fertilization IMP
IMP: 通过突变表型推断
24739963 MGI
involved in sperm-egg recognition IMP
IMP: 通过突变表型推断
24739963 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in acrosomal membrane IDA
IDA: 通过直接分析推断
19144954 MGI
located in acrosomal vesicle IDA
IDA: 通过直接分析推断
20421979 MGI
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
35960805 MGI
located in membrane IDA
IDA: 通过直接分析推断
15759005 MGI
is active in plasma membrane IDA
IDA: 通过直接分析推断
35960805 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
27624483 MGI
located in plasma membrane IMP
IMP: 通过突变表型推断
27309808 MGI
part of protein complex involved in cell-cell adhesion IDA
IDA: 通过直接分析推断
31672133 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

izumo sperm-egg fusion protein 1

OBF

oocyte binding/fusion factor

sperm-specific protein Izumo

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07004 IZUMO1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07005 IZUMO1R Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19263 Izumo1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21242 Izumo1r Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25752 Izumo1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27759 Izumo1r Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Izumo1 NCBI NCBI:284359
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