1. Gene
  2. Txn2 - thioredoxin 2 Gene

Txn2 - thioredoxin 2 Gene

种属: Rattus norvegicus

基因 ID: 79462 | 基因类型: protein coding

关于 Txn2

功能概要

Contributes to peptide-methionine (R)-S-oxide reductase activity; peptide-methionine (S)-S-oxide reductase activity; and protein-disulfide reductase activity. Involved in several processes, including response to axon injury; response to glucose; and response to hypoxia. Located in dendrite; mitochondrion; and neuronal cell body. Human ortholog(s) of this gene implicated in combined Oxidative Phosphorylation deficiency 29. Orthologous to human TXN2 (thioredoxin 2). [provided by Alliance of Genome Resources, Apr 2022]

Txn2 基因产物(1)

mRNA Protein Name
NM_053331.2 NP_445783.1 thioredoxin, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
contributes to peptide-methionine (R)-S-oxide reductase activity IDA
IDA: 通过直接分析推断
18452709 RGD
contributes to peptide-methionine (S)-S-oxide reductase activity IDA
IDA: 通过直接分析推断
18452709 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
16774913 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
18452709 RGD
contributes to protein-disulfide reductase activity IDA
IDA: 通过直接分析推断
9006939 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to nutrient levels IEP
IEP: 通过表达模式推断
18578693 RGD
involved in response to axon injury IEP
IEP: 通过表达模式推断
18441302 RGD
involved in response to glucose IEP
IEP: 通过表达模式推断
15039483 RGD
involved in response to hormone IEP
IEP: 通过表达模式推断
10792444 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
15468176 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
18790005 RGD
involved in response to oxidative stress IEP
IEP: 通过表达模式推断
18441302 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
17253623 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendrite IDA
IDA: 通过直接分析推断
20620191 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
20620191 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

thioredoxin, mitochondrial

MTRX

mt-Trx

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Txn2 NCBI NCBI:25828