2. Gene
  3. Sf3b1 - splicing factor 3b, subunit 1 Gene

Sf3b1 - splicing factor 3b, subunit 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: TA-8; Prp10; Targ4; 155kDa; SAP155; SF3b155; 2810001M05Rik

基因 ID: 81898 | 基因类型: protein coding

关于 Sf3b1

功能概要

Enables chromatin binding activity. Acts upstream of or within anterior/posterior pattern specification; blastocyst formation; and mRNA splicing, via spliceosome. Located in chromatin and nuclear matrix. Part of U2 snRNP. Is expressed in several structures, including central nervous system; endocrine gland; genitourinary system; hemolymphoid system gland; and sensory organ. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and myelodysplastic syndrome. Orthologous to human SF3B1 (splicing factor 3b subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Sf3b1 基因产物(1)

mRNA Protein Name
NM_031179.2 NP_112456.2 splicing factor 3B subunit 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
15741318 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15741318 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within anterior/posterior pattern specification IGI
IGI: 通过遗传相互作用推断
15741318 MGI
acts upstream of or within blastocyst formation IMP
IMP: 通过突变表型推断
23211737 MGI
acts upstream of or within mRNA splicing, via spliceosome IMP
IMP: 通过突变表型推断
23211737 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
20153721 MGI
located in nuclear matrix IDA
IDA: 通过直接分析推断
20153721 MGI
located in nucleus IDA
IDA: 通过直接分析推断
20153721 MGI
part of small nuclear ribonucleoprotein complex IDA
IDA: 通过直接分析推断
20153721 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

splicing factor 3B subunit 1

SAP 155

pre-mRNA-splicing factor SF3b 155 kDa subunit

spliceosome-associated protein 155

splicing factor 3b, subunit 1, 155 kDa

transforming growth factor alpha regulated gene 4

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-111517 H3B-8800 Inhibitor 98.85% Phase 1
Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-16399 Pladienolide B Inhibitor 99.20% 否
HY-16466 Spliceostatin A 95.09% 否
HY-141881 PROTAC-O4I2 Degrader 99.56% 否
HY-168534 WX-02-43 Ligand 99.88% 否
HY-181421 WX-02-23 Modulator / 否
HY-133924 18-Deoxyherboxidiene Inhibitor / 否
HY-122637 Sudemycin K Inhibitor / 否
HY-15867 Meayamycin B Inhibitor / 否
HY-120907 Sudemycin E Ligand / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sf3b1 NCBI NCBI:23451
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