2. 疾病领域
  3. 神经系统疾病
  4. 神经退行性疾病
  5. 阿尔茨海默病 帕金森病
  6. MD-230254

MD-230254 是一种可逆、竞争性且选择性的 MAO-B 抑制剂，其 IC50 值为 1.8 nM。MD-230254 可用于研究与 MAO-B 相关的神经退行性疾病，包括帕金森病和阿尔茨海默病。

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MD-230254

MD-230254 Chemical Structure

CAS No. : 147807-20-3

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MD-230254 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MD-230254 is a reversible, competitive and selective inhibitor inhibitor of MAO-B with an IC50 value of 1.8 nM. MD-230254 can be used for the study of MAO-B-related neurodegenerative diseases including Parkinson’s disease and Alzheimer’s disease[1][2].

体外研究
(In Vitro)

MD-230254 可强效且选择性地抑制大鼠肝线粒体组分中的单胺氧化酶 B (MAO-B)，其 IC50 为 1.8 nM，MAO-A/MAO-B 选择性比值 >56,000[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

MD-230254 相关抗体:
分子量

321.33

Formula

C18H15N3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MD-230254 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MD-230254147807-20-3MD230254MD 230254parkinson's diseaseratdepressionrat liver mitochondria fractionMAO-Bmonoamine oxidase Bpsychiatric disordersMAO-AInhibitorinhibitorinhibit

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