1. 多肽产品
  2. 多肽合成
  3. 氨基酸及其衍生物
  4. Montanastatin

Montanastatin 是一种抗肿瘤剂,可以从陆生放线菌 Streptomyces anulatus 中分离得到。Montanastatin 可抑制多种癌细胞的生长。Montanastatin 可用于淋巴细胞白血病、卵巢癌、脑癌、肾癌、肺癌、结肠癌和黑色素瘤的相关研究。

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Custom Peptide Synthesis

Montanastatin

Montanastatin Chemical Structure

CAS No. : 14410-23-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Montanastatin is an antitumor agent that can be isolated from the terrestrial actinomycete Streptomyces anulatus. Montanastatin inhibits the growth of various cancer cells. Montanastatin can be used in research related to lymphocytic leukemia, ovarian cancer, brain cancer, renal cancer, lung cancer, colon cancer and melanoma[1][2].

体外研究
(In Vitro)

Montanastatin (Compound 1) 可抑制小鼠 P388 白血病细胞及多种人类癌细胞系的生长,其中小鼠 P388 白血病细胞的 GI50 = 7.5 μg/mL,人类癌细胞系包括 OVCAR-3 (GI50 = 1.2 μg/mL)、SF-295 (GI50 = 3.3 μg/mL)、A-498 (GI50 = 2.0 μg/mL)、NCI-H460 (GI50 = 1.4 μg/mL)、KM20L2 (GI50 = 1.4 μg/mL) 和 SK-MEL-5 (GI50 = 1.3 μg/mL)[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

740.88

Formula

C36H60N4O12

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Montanastatin
目录号:
HY-182259
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