2. Others
  3. Biochemical Assay Reagents
  4. MTL-005

MTL-005 是一种含硼的放射增敏剂，用于硼中子俘获疗法 (BNCT)。MTL-005通过富集硼-10 同位素于肿瘤组织，在热中子照射下发生核裂变，释放高线性能量转移 (LET) 的 α 粒子和锂离子，选择性摧毁肿瘤细胞，同时最小化对周围正常组织的损伤。MTL-005 在 SCCVII 鳞状细胞癌小鼠模型显著控制了肿瘤的进程，延长小鼠的存活期。MTL-005 可用于研究头颈癌等实体瘤。

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MTL-005

MTL-005 Chemical Structure

CAS No. : 1030303-53-7

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MTL-005 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MTL-005 is a boron-containing radiosensitizer used in Boron Neutron Capture Therapy (BNCT). MTL-005 enriches the boron-10 isotope in tumor tissues, causing nuclear fission under thermal neutron irradiation, releasing high linear energy transfer (LET) α particles and lithium ions, which selectively destroy tumor cells while minimizing damage to surrounding normal tissues. MTL-005 significantly controlls the tumor progression in the SCCVII squamous cell carcinoma mouse model and prolonged the survival of the mice. MTL-005 can be used to study solid tumors such as head and neck cancer.

分子量

958.54

Formula

C38H42B20CuN6O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MTL-005 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MTL-0051030303-53-7MTL005MTL 005Biochemical Assay Reagentsboron neutron capture therapy (BNCT)radiosensitizerSCCVII murine modeltumor boron concentrationphase 1 clinical trialInhibitorinhibitorinhibit

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产品名称：
MTL-005
目录号：
HY-19938
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