2. Others Cell Cycle/DNA Damage Epigenetics Anti-infection
  3. Reference Standards Sirtuin HBV
  4. OSS_128167 (Standard)

OSS_128167 (Standard) 是 OSS_128167 (HY-107454) 的分析标准品。本产品用于研究及分析应用。OSS_128167 是一种有效的选择性沉默调节蛋白 6 (SIRT6) 抑制剂，对 SIRT6，SIRT1 和 SIRT2 的 IC50 分别为 89 μM，1578 μM 和 751 μM。OSS_128167 具有抗 HBV 活性，可抑制 HBV 的转录和复制。OSS_128167 具有抗癌，抗炎和抗病毒作用。

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OSS_128167 (Standard)

OSS_128167 (Standard) Chemical Structure

CAS No. : 887686-02-4

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OSS_128167 (Standard) 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

OSS_128167 (Standard) is the analytical standard of OSS_128167 (HY-107454). This product is intended for research and analytical applications. OSS_128167 is a potent selective sirtuin 6 (SIRT6) inhibitor with IC50s of 89 μM, 1578 μM and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-HBV activity that inhibits HBV transcription and replication. OSS_128167 has anti-cancer, anti-inflammation and anti-viral effects[1][2].

IC50 & Target

IC50: 89 μM (SIRT6), 1578 μM (SIRT1), 751 μM (SIRT2)[1]
分子量

366.32

Formula

C19H14N2O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

OSS_128167 (Standard) 相关分类

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

OSS_128167 (Standard)887686-02-4Reference StandardsSirtuinHBVHepatitis B virusSIRT6deacetylasediabetesimmuneanti-cancerH3K9acetylationGLUT-1TNF-αchemosensitizationantiviralPPARαInhibitorinhibitorinhibit

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