2. GPCR/G Protein Neuronal Signaling
  3. mAChR Adrenergic Receptor
  4. p-F-HHSiD

p-F-HHSiD (p-Fluorohexahydrosiladifenidol) 是一种强效且选择性的 M3 毒蕈碱型乙酰胆碱受体 (M3 mAChR) 拮抗剂。p-F-HHSiD 对 M 受体的其他亚型以及 α1-肾上腺素受体 (alpha1-adrenoceptor) 具有拮抗作用。p-F-HHSiD 可用于癌症、代谢性疾病、神经系统疾病和心血管疾病的研究，如结肠癌、阿尔茨海默病和糖尿病。

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p-F-HHSiD

p-F-HHSiD Chemical Structure

CAS No. : 116679-83-5

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p-F-HHSiD 的其他形式现货产品:

Customer Review

Other Forms of p-F-HHSiD:

p-F-HHSiD 相关抗体

Top Publications Citing Use of Products

查看 mAChR 亚型特异性产品:

查看所有亚型
mAChR1 mAChR2 mAChR3 mAChR4 mAChR5

查看 Adrenergic Receptor 亚型特异性产品:

查看所有亚型
α adrenergic receptor β adrenergic receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

p-F-HHSiD (p-Fluorohexahydrosiladifenidol) is a potent and selective M3 mAChR antagonist. p-F-HHSiD has antagonistic effects on other subtypes of the M receptor and the alpha1-adrenoceptor. p-F-HHSiD can be used for the researches of cancer, metabolic, neurological and cardiovascular disease such as, colon cancer, Alzheimer’s disease and diabetes[1][2][3][4][5][6].

IC50 & Target[1][2][3][4][5][6]

mAChR1

 

mAChR2

 

mAChR3

 

mAChR4

 

mAChR5

 

α1-adrenergic receptor

 

分子量

349.56

Formula

C20H32FNOSi
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

p-F-HHSiD 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

p-F-HHSiD116679-83-5p-FluorohexahydrosiladifenidolmAChRAdrenergic ReceptorMuscarinic acetylcholine receptorBeta ReceptorM3 mAChRM receptorAlpha(1)-adrenoceptorColon cancerH508Alzheimer’s diseaseAchDiabetesInhibitorinhibitorinhibit

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