2. Others Metabolic Enzyme/Protease
  3. Reference Standards Proteasome
  4. Proteasome inhibitor IX (Standard)

Proteasome inhibitor IX (Standard) 是 Proteasome inhibitor IX (HY-107412) 的分析标准品。本产品用于研究及分析应用。Proteasome inhibitor IX (PS-IX; AM114) 是一种 Chalcone 衍生物，也是一种 20S 蛋白酶体 (20S proteasome) 的胰凝乳蛋白酶样活性抑制剂，IC50 值约为 1 μM。Proteasome inhibitor IX 具有 HCT116 p53+/+ 细胞生长抑制活性，IC50 值为 1.49 μM，具有有效的抗癌活性。

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Proteasome inhibitor IX (Standard)

Proteasome inhibitor IX (Standard) Chemical Structure

CAS No. : 856849-35-9

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生物活性

Proteasome inhibitor IX (Standard) is the analytical standard of Proteasome inhibitor IX (HY-107412). This product is intended for research and analytical applications. Proteasome inhibitor IX (PS-IX; AM114) is a Chalcone derivative and a chymotrypsin-like activity of the 20S proteasome inhibitor with an IC50 value of ~1 μM. Proteasome inhibitor IX exhibits HCT116 p53+/+ cells growth inhibitory activity with an IC50 value of 1.49 μM. Proteasome inhibitor IX has potent anticancer activity[1][2].

IC50 & Target

IC50: 1 μM (20S proteasome)[1]
分子量

377.01

Formula

C20H21B2NO5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Proteasome inhibitor IX (Standard) 相关分类

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Keywords:

Proteasome inhibitor IX (Standard)856849-35-9Reference StandardsProteasomeAnticancerboronicacidEGCGcytotoxicChalconep53chymotrypsin-like20SubiquitinatedInhibitorinhibitorinhibit

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