AADAT/alpha-Aminoadipate Aminotransferase 蛋白, Human (His-SUMO)

The α-aminoadipic acid aminotransferase protein exhibits broad substrate specificity, preferentially selecting aminoadipic acid, kynurenine, methionine, and glutamate as an aminotransferase. It also exhibits transaminase activity toward tryptophan, aspartate, and hydroxykynurenine, and accepts oxygen-containing acids such as 2-oxoglutarate, 2-oxohexanoic acid, phenylpyruvate, and α- Oxo-γ-methylmercaptanbutyric acid. AADAT/alpha-Aminoadipate Aminotransferase Protein, Human (His-SUMO) is the recombinant human-derived alpha-Aminoadipate Aminotransferase protein, expressed by E. coli , with N-6*His-SUMO tag.

α-氨基己二酸转氨酶蛋白表现出广泛的底物特异性，作为转氨酶对氨基己二酸、犬尿氨酸、蛋氨酸和谷氨酸具有活性。该酶还对色氨酸、天冬氨酸和羟基犬尿氨酸表现出转氨酶活性。此外，它接受各种含氧酸作为氨基受体，优选2-氧代戊二酸、2-氧代己酸、苯基丙酮酸和α-氧代-γ-甲硫醇丁酸。值得注意的是，α-氨基己二酸氨基转移酶可以在体外利用乙醛酸作为氨基受体，显示出其在酶促反应中接受不同底物的多功能性。

Human

E. coli

N-SUMO;N-6*His

Q8N5Z0-1 (P30-L425)

51166  [NCBI]

Full Length of Mature Protein

≥ 90%, as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.