2. Others GPCR/G Protein Neuronal Signaling
  3. Reference Standards Neurokinin Receptor
  4. SB 218795 (Standard)

SB 218795 (Standard) 是 SB 218795 (HY-107692) 的分析标准品。本产品用于研究及分析应用。SB 218795 是一种有效的选择性非肽 NK3 受体拮抗剂，对 hNK3 的 Ki 值为 13 nM。SB 218795 对 hNK3 的选择性分别比 hNK2 和 hNK1 高 90 倍和 7000 倍。SB 218795 可以抑制 NK3 受体介导的兔瞳孔收缩。

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SB 218795 (Standard)

SB 218795 (Standard) Chemical Structure

CAS No. : 174635-53-1

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SB 218795 (Standard) 相关抗体

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生物活性

SB 218795 (Standard) is the analytical standard of SB 218795 (HY-107692). This product is intended for research and analytical applications. SB 218795 is a potent and selective non-peptide NK3 receptor antagonist, with a Ki 13 nM for hNK3. SB 218795 shows about 90-fold and 7000-fold selectivity for hNK3 over hNK2 and hNK1, respectively. SB 218795 can inhibit NK3 receptor-mediated pupillary constriction of the rabbit[1][2].

分子量

396.44

Formula

C25H20N2O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SB 218795 (Standard) 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SB 218795 (Standard)174635-53-1Reference StandardsNeurokinin ReceptorNK receptorTachykinin receptorneurokinin-3NK-3pupillaryconstrictionInhibitorinhibitorinhibit

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