2. Others Apoptosis Anti-infection Metabolic Enzyme/Protease
  3. Fungal Isotope-Labeled Compounds HIV Bacterial Endogenous Metabolite Ferroptosis Apoptosis
  4. Trigonelline-d3-1 chloride

Trigonelline-d3-1 chloride  (Synonyms: 葫芦巴碱盐酸盐-d3; Trigonelline-d3-1 hydrochloride)

目录号: HY-N0415S1
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Trigonelline-d3-1 chloride (Trigonelline-d3-1 hydrochloride) 是氘代标记的 Trigonelline chloride (HY-N0415)。Trigonelline chloride 是一种具有潜在抗糖尿病活性的生物碱，能够从葫芦巴或益母草中分离得到。Trigonelline chloride 是一种有效的 Nrf2 抑制剂，可阻断 Nrf2 依赖的蛋白酶体活性，从而增强胰腺癌细胞凋亡 (apoptosis)。Trigonelline chloride 还具有抗 HSV-1 、抗细菌、抗真菌活性，可诱导铁死亡 (ferroptosis)。

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Trigonelline-d<sub>3</sub>-1 chloride

Trigonelline-d3-1 chloride Chemical Structure

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Other Forms of Trigonelline-d3-1 chloride:

Trigonelline-d3-1 chloride 相关抗体

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生物活性

Trigonelline-d3-1 chloride (Trigonelline-d3-1 hydrochloride) is the deuterium labeled Trigonelline chloride (HY-N0415). Trigonelline chloride is an alkaloid with potential antidiabetic activity that can be isolated from Trigonella foenum-graecum L or Leonurus artemisia. Trigonelline chloride is a potent Nrf2 inhibitor that blocks Nrf2-dependent proteasome activity, thereby enhancing apoptosis in pancreatic cancer cells. Trigonelline chloride also has anti-HSV-1, antibacterial, and antifungal activity, and induces ferroptosis.

产品应用

1. 该化合物可作为示踪剂。
2. 该化合物可作为 NMR、GC-MS 或 LC-MS 分析中的内标品，用于定量分析。
体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Trigonelline-d3-1 chloride 相关抗体:
分子量

190.64

Formula

C8H7D3ClNO2
非标记 CAS
中文名称

盐酸葫芦巴碱-d3；葫芦巴碱盐酸盐-d3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Trigonelline-d3-1 chloride 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trigonelline-d3-1盐酸葫芦巴碱-d3葫芦巴碱盐酸盐-d3FungalIsotope-Labeled CompoundsHIVBacterialEndogenous MetaboliteFerroptosisApoptosisHuman immunodeficiency virusInhibitorinhibitorinhibit

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