2. Others Metabolic Enzyme/Protease
  3. Reference Standards Acyltransferase
  4. VULM 1457 (Standard)

VULM 1457 (Standard) 是 VULM 1457 (HY-107571) 的分析标准品。本产品用于研究及分析应用。VULM 1457 是一种有效的胆固醇酰基转移酶 (acyl-CoA) 抑制剂。VULM1457 显着降低肾上腺髓质素 (AM) 的产生和分泌，并下调人肝母细胞上的 AM 受体。VULM 1457 具有显着的降血脂活性，并改善了整体心肌缺血再灌注损伤结果。VULM 1457 具有研究糖尿病和高胆固醇血症的潜力。

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VULM 1457 (Standard)

VULM 1457 (Standard) Chemical Structure

CAS No. : 228544-65-8

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VULM 1457 (Standard) 相关抗体

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ACAT1 ACAT2 MGAT2 ACAT DGAT1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

VULM 1457 (Standard) is the analytical standard of VULM 1457 (HY-107571). This product is intended for research and analytical applications. VULM 1457 is a potent inhibitor of cholesterol acyltransferase (acyl-CoA). VULM1457 significantly reduces production and secretion of adrenomedullin (AM) and down-regulates AM receptors on human hepatoblastic cells. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM 1457 has the potential for the research of diabetes mellitus and hypercholesterolaemia[1][2].

IC50 & Target

acyl-CoA[1]
分子量

449.57

Formula

C25H27N3O3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

VULM 1457 (Standard) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VULM 1457 (Standard)228544-65-8Reference StandardsAcyltransferaseDiacylglycerol acyltransferaseDiglyceride acyltransferaseacyl-CoA:cholesterol acyltransferasemono- acylglycerol acyltransferasecholesterol acyltransferaseacyl-CoAhypolipidaemicdiabetes mellitushypercholesterolaemiamyocardialischaemia-reperfusionInhibitorinhibitorinhibit

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