2. Metabolic Enzyme/Protease Others
  3. Angiotensin-converting Enzyme (ACE) Drug Intermediate
  4. VYPFPGPIHN

VYPFPGPIHN 是一种 β-casomorphin (HY-P0179) 的前体肽，也是一种 ACE 抑制剂 (IC50 = 123 μM)。VYPFPGPIHN 可抵抗肠细胞单层相关肽酶的水解，维持结构完整性与 ACE 抑制活性。VYPFPGPIHN 不会被分化的肠细胞单层大量摄取或转运。

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Custom Peptide Synthesis

VYPFPGPIHN

VYPFPGPIHN Chemical Structure

CAS No. : 157173-35-8

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VYPFPGPIHN 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

VYPFPGPIHN is a precursor peptide of β-casomorphin (HY-P0179) and also an ACE inhibitor (IC50 = 123 μM). VYPFPGPIHN resists hydrolysis by peptidases associated with intestinal cell monolayers, maintaining structural integrity and ACE inhibitory activity. VYPFPGPIHN is not extensively taken up or transported by differentiated intestinal cell monolayers[1].

体外研究
(In Vitro)

VYPFPGPIHN (500 μM; 120 min) 与分化的 Caco-2 细胞单层共孵育后，其 ACE 抑制活性未发生改变，且未检测到该肽跨单层的转运[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

VYPFPGPIHN 相关抗体:
分子量

1140.29

Formula

C56H77N13O13
CAS 号
Sequence

Val-Tyr-Pro-Phe-Pro-Gly-Pro-Ile-His-Asn
Sequence Shortening

VYPFPGPIHN
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

VYPFPGPIHN 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VYPFPGPIHN157173-35-8Angiotensin-converting Enzyme (ACE)Drug IntermediateDrug Iintermediateintestinal cell monolayer-associated peptidasesACECaco-2 cell monolayersintestinal cell monolayersInhibitorinhibitorinhibit

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产品名称：
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目录号：
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