2. Immunology/Inflammation
  3. Cyclophilin
  4. ZX-J-19L

ZX-J-19L 是一种 CyPJ 抑制剂，对多种肿瘤细胞系具有抑制活性。ZX-J-19L 可在体外抑制人肝癌细胞、人乳腺癌、卵巢癌和前列腺癌细胞的生长。ZX-J-19L 可用于肿瘤的研究。

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ZX-J-19L

ZX-J-19L Chemical Structure

CAS No. : 1346754-06-0

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ZX-J-19L 相关抗体

Top Publications Citing Use of Products

查看 Cyclophilin 亚型特异性产品:

查看所有亚型
Cyclophilin A Cyclophilin B Cyclophilin C Cyclophilin D Cyclophilin G Cyclophilin E

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ZX-J-19L is a CyPJ inhibitor with inhibitory activity against a variety of tumor cell lines. ZX-J-19L inhibits the growth of human liver cancer cells, human breast cancer cells, ovarian cancer cells and prostate cancer cells in vitro. ZX-J-19L can be used for tumor research[1].

体外研究
(In Vitro)

ZX-J-19L (1.0-250 µM; 48 h) 可抑制人肝癌 SK-HEP1、QGY 细胞的增殖[1]。
ZX-J-19L (20 µM; 48 h) 可抑制人乳腺癌 (HCC1954、BT474、MDA-MB468)、卵巢癌 (SKOV3) 及前列腺癌 (PC3、LNCaP) 细胞生长[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

ZX-J-19L 相关抗体:

Cell Proliferation Assay[1]

Cell Line: human hepatocellular carcinoma (HCC) SK-HEP1/QGY cells
Concentration: 1.0, 5.0, 10, 50, 250 µM
Incubation Time: 48 h
Result: Inhibited SK-HEP1 cell growth with an IC50 of 3.512 µM.
Inhibited QGY cell growth with an IC50 of 21.353 µM.

Cell Proliferation Assay[1]

Cell Line: human breast cancer HCC1954, BT474, MDA-MB468 cells; human ovarian cancer SKOV3 cells; human prostate cancer PC3, LNCaP cells
Concentration: 20 µM
Incubation Time: 48 h
Result: Inhibited HCC1954 cell growth by 91.258%.
Inhibited BT474 cell growth by 90.963%.
Inhibited MDA-MB468 cell growth by 90.849%.
Inhibited SKOV3 cell growth by 90.919%.
Inhibited PC3 cell growth by 91.039%.
Inhibited LNCaP cell growth by 91.038%.
分子量

367.44

Formula

C24H21N3O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ZX-J-19L 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ZX-J-19L1346754-06-0Cyclophilinhuman ovarian cancer cellsQGY cellsHCC1954 cellsBT474 cellshuman hepatocellular carcinoma cellshuman prostate cancer cellshuman breast cancer cellscyclophilin JSK-HEP1 cellsCyPJInhibitorinhibitorinhibit

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产品名称：
ZX-J-19L
目录号：
HY-182397
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