产品货号：C987675
产品名称：2-(2-Cyanophenyl)-1,3,2-dioxaborinane
Synonyms:2-(1,3,2-Dioxaborinan-2-yl)benzonitrile;
CAS号：172732-52-4
分子式：C₁₀H₁₀BNO₂
Appearance:White to Pale Beige Solid
Melting Point:54-56°C
分子量：187
Storage:4°C, Hygroscopic
Solubility:Chloroform (Slightly), Methanol (Slightly)
Stability
Hygroscopic
Category:Building Blocks; Miscellaneous;
应用：2-(2-Cyanophenyl)-1,3,2-dioxaborinane is used in the synthesis of AMPA receptor antagonists in the treatment of neurological diseases causing dysfunction of glutamatergic neurotransmission. Also used in the small scale synthesis of Perampanel (P285520), an AMPA receptor antagonist.
参考文献：Hibi, S. et al.: J. Med. Chem., 55, 10584 (2012); McElhinny, C. et al.: Synthesis, 44, 57 (2012);
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