产品货号：A158340
产品名称：trans-4-Acetamidocyclohexanol
Synonyms:trans-N-(4-Hydroxycyclohexyl)-acetamide;
CAS号：27489-60-7
分子式：C₈H₁₅NO₂
Appearance:White to Off-White Solid
Melting Point:127 - 144°C
分子量：157.21
Storage:-20°C, Inert atmosphere
Solubility:Dichloromethane (Slightly, Heated), DMSO (Slightly), Methanol (Slightly), Water
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用：trans-4-Acetamidocyclohexanol is an intermediate in the synthesis of 4”-trans-Hydroxy Cilostazol (H918300), a metabolite of Cilostazol (C441500), a potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogeni, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo.
参考文献：de Morais, S., et al.: J. Biol. Chem., 269, 15419 (1994); Tata, P; J Pharm Biomed Anal, 24, 381
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