产品货号：A632005
产品名称：4-Amino-3,5-dichloropyridine N-Oxide
Synonyms:3,5-Dichloro-4-aminopyridine N-Oxide; 3,5-Dichloro-4-pyridinamine 1-Oxide;
CAS号：91872-02-5
分子式：C₅H₄Cl₂N₂O
分子量：179
Category:Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用：4-Amino-3,5-dichloropyridine N-Oxide is the impurity of the drug Roflumilast (R639700), which is a selective phosphodiesterase 4(PDE4) inhibitor, antiasthmatic.
参考文献：Hatzelmann, A., et al.: J. Pharmacol. Exp. Ther., 297, 267 (2001); Schmidt, B.M.W., et al.: J. Allergy Clin. Immunol., 108, 530 (2001); Timmer, W., et al.: J. Clin. Pharmacol., 42, 297 (2002); Rabe, K.F., et al.: Lancet, 366, 563 (2005);
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