产品货号:B679125
产品名称:7-Bromoacetylaminocephalosporanic Acid
Synonyms:(6R-trans)-3-[(Acetyloxy)methyl]-7-[(bromoacetyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; 7-(2-Bromoacetamido)cephalosporanic Acid;
CAS号:26973-80-8
分子式:C₁₂H₁₃BrN₂O₆S
Appearance:Off-white Solid
分子量:393.21
Storage:4°C, Inert atmosphere, Light sensitive
Solubility:Chloroform, Dichloromethane, Dimethyl Sulfoxide
Category:Standards; Chiral Molecules; Sulfhydryl Active Reagents; Pharmaceutical/API Drug Impurities/Metabolites;
应用:An analog of glutaryl-7-amino cephalosporanic acid (GL-7-ACA). Can inhibit and specifically alkylate GL-7-ACA acylase (C130) from Pseudomonas sp.130 by forming a carbon-carbon bond between BA-7-ACA and the C-2 on indole ring of Trp-b4 residue of C130.
参考文献:Zhang, W. et al.; Biochem. Bioph. Res. Co. 313, 555 (2004); Huang, X. et al.; J. Biol. Chem. 277, 10256 (2002)
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