2. Anti-infection
  3. Bacterial Fungal
  4. 1-Methyl-4-nitroimidazole

1-Methyl-4-nitroimidazole 是一种抗菌剂。1-Methyl-4-nitroimidazole 可被细菌硝基还原酶还原，形成有毒衍生物，这些衍生物会造成 DNA 损伤、抑制细菌核酸合成、通过还原自由基阴离子的无效循环产生有毒超氧化物，并诱导细菌细胞死亡。1-Methyl-4-nitroimidazole 对细菌 (bacteria) 和真菌 (fungal) 表现出中等强度的体外活性。1-Methyl-4-nitroimidazole 可用于皮肤感染、化脓性感染和尿路感染的研究。

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1-Methyl-4-nitroimidazole

1-Methyl-4-nitroimidazole Chemical Structure

CAS No. : 3034-41-1

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1-Methyl-4-nitroimidazole 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

1-Methyl-4-nitroimidazole is an antibacterial agent. 1-Methyl-4-nitroimidazole is reduced by bacterial nitroreductases to form toxic derivatives, which cause DNA damage, inhibit bacterial nucleic acid synthesis, generate toxic superoxides through futile cycling of reduced radical anions, and induce bacterial cell death. 1-Methyl-4-nitroimidazole exhibits moderate in vitro activity against bacteria and fungal. 1-Methyl-4-nitroimidazole can be used in the research of skin infections, purulent infections and urinary tract infections[1].

体外研究
(In Vitro)

1-Methyl-4-nitroimidazole (1-methyl-4-nitro-1H-imidazole) (24-48 h) 对受试的革兰氏阳性菌、革兰氏阴性菌和真菌分离株具有中等活性，对 Staphylococcus aureus AB 188 的最大抑菌圈为 18 mm，对 Candida tropicalis 的最大抑菌圈为 18 mm[1]。
1-Methyl-4-nitroimidazole (100-300 μg/mL; 24 h) 可抑制受试革兰氏阳性菌、革兰氏阴性菌及真菌分离株的生长，其 MIC 值范围为 100-300 μg/mL[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

1-Methyl-4-nitroimidazole 相关抗体:
分子量

127.10

Formula

C4H5N3O2
CAS 号
性状

固体

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
纯度 & 产品资料
参考文献

1-Methyl-4-nitroimidazole 相关分类

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Keywords:

1-Methyl-4-nitroimidazole3034-41-1BacterialFungalantibacterial agentskin infectionspurulent infectionsurinary tract infectionsStaphylococcus aureusCandida tropicalisInhibitorinhibitorinhibit

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