1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. GABA Receptor
  3. 5-Deoxykievitone

5-Deoxykievitone 是一种可于 Phaseolus 属中发现的异黄烷酮,同时也是 GABA 受体调节剂。5-Deoxykievitone 可通过 α1β2γ2s GABAA 受体增强 GABA 诱导的氯离子电流。5-Deoxykievitone 可用于癫痫及焦虑的相关研究。

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5-Deoxykievitone

5-Deoxykievitone Chemical Structure

CAS No. : 74161-24-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

5-Deoxykievitone, an isoflavanone found in Phaseolus species, is a GABA receptor modulator. 5-Deoxykievitone potentiates GABA-induced chloride current through α1β2γ2s GABAA receptors. 5-Deoxykievitone can be used for the research of epilepsy and anxiety[1][2].

体外研究
(In Vitro)

5-Deoxykievitone (Compound 10) (100 μM) 可增强表达 α1β2γ2s GABAA 受体的非洲爪蟾卵母细胞中 GABA 诱导的氯离子电流,在 100 μM 浓度下的平均增强率达 361.45%[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

340.38

Formula

C20H20O5

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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产品名称:
5-Deoxykievitone
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HY-N15436
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