1. Signaling Pathways
  2. Anti-infection
  3. Measles Virus

Measles Virus 

MeV

Measles virus is a highly contagious negative strand RNA virus that is transmitted via the respiratory route and causes systemic disease in previously unexposed humans and non-human primates. Measles is characterised by fever and skin rash and usually associated with cough, coryza and conjunctivitis. A hallmark of measles is the transient immune suppression, leading to increased susceptibility to opportunistic infections. At the same time, the disease is paradoxically associated with induction of a robust virus-specific immune response, resulting in lifelong immunity to measles.

Measles Virus 相关产品 (1):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-117121
    MeV-IN-1 Inhibitor
    MeV-IN-1 (OX-1) 是一种特异性抑制麻疹病毒 (MeV) 进入细胞的抑制剂,其 IC50 值为 100 μM。MeV-IN-1 对活体 MeV-Edm 病毒的 IC50 值为 55 μM。MeV-IN-1 可有效抑制感染灶的形成。MeV-IN-1 几乎没有细胞毒性。MeV-IN-1 可有效抑制在表达 MV-H 和 MV-F 蛋白的细胞中 R18 的重新分布,从而阻止细胞膜融合。
    MeV-IN-1