1. Anti-infection
  2. Fungal
  3. Aminopyrifen

Aminopyrifen 是一种 GWT-1 抑制剂。Aminopyrifen 可抑制磷脂酰肌醇的肌醇酰化,破坏 GPI 锚定蛋白的成熟过程与真菌细胞壁完整性。Aminopyrifen 能强烈抑制灰葡萄孢的芽管伸长,延缓孢子萌发,阻止附着胞形成,并阻断病原菌对植物组织的侵染。Aminopyrifen 对茄子灰霉病和黄瓜白粉病的田间种群有效,可用于灰霉病、白粉病等多种植物真菌病害的研究。

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Aminopyrifen

Aminopyrifen Chemical Structure

CAS No. : 1531626-08-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Aminopyrifen is a GWT-1 inhibitor. Aminopyrifen inhibits the inositol acylation of phosphatidylinositol, disrupting the maturation process of GPI-anchored proteins and the integrity of fungal cell walls. Aminopyrifen strongly inhibits germ tube elongation of Botrytis cinerea, delays spore germination, prevents appressorium formation, and blocks the infection of plant tissues by pathogenic fungi. Aminopyrifen is effective against field populations of eggplant gray mold and cucumber powdery mildew, and can be used for research on various plant fungal diseases such as gray mold and powdery mildew[1].

体外研究
(In Vitro)

Aminopyrifen 可强效抑制多数受试子囊菌及相关无性型真菌的菌丝径向生长 (EC50: 0.0039-0.23 mg/L),对担子菌的活性存在差异,且对卵菌瓜果腐霉无活性[1]
Aminopyrifen (20 小时) 不抑制灰葡萄孢的孢子萌发 (EC50: >10 mg/L),但可强效抑制芽管伸长 (EC50: 0.035 mg/L) 并诱导芽管形态肿胀[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

334.37

Formula

C20H18N2O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Aminopyrifen
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HY-182471
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