Ccr3 - chemokine (C-C motif) receptor 3 Gene

中文名称：趋化因子 (CC 基序) 受体 3

种属: Mus musculus

同用名: CKR3; Cmkbr3; CC-CKR3; Cmkbr1l2

关于 Ccr3

功能概要

该基因编码的蛋白可启动 CC 趋化因子结合活性和 CC 趋化因子受体活性。参与血管生成的正向调节和内皮细胞增殖的正向调节。在趋化性上游或趋化性内起作用。预计位于核内体；细胞外空间；和质膜。预计在细胞质和质膜外侧有活性。在胚胎和卵黄囊中表达。与哮喘有关的该基因的人类直系同源物；卵巢上皮癌；和鼻炎。与人 CCR3（CC 基序趋化因子受体 3）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables C-C chemokine binding activity and C-C Chemokine Receptor activity. Involved in positive regulation of angiogenesis and positive regulation of endothelial cell proliferation. Acts upstream of or within chemotaxis. Predicted to be located in endosome; extracellular space; and plasma membrane. Predicted to be active in cytoplasm and external side of plasma membrane. Is expressed in embryo and yolk sac. Human ortholog(s) of this gene implicated in asthma; ovary epithelial cancer; and rhinitis. Orthologous to human CCR3 (C-C motif Chemokine Receptor 3). [provided by Alliance of Genome Resources, Apr 2022]