2. Gene
  3. Tg - thyroglobulin Gene

Tg - thyroglobulin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Tgn; cog

基因 ID: 21819 | 基因类型: protein coding

关于 Tg

功能概要

Enables identical protein binding activity. Involved in thyroid hormone generation. Acts upstream of or within iodide transport; regulation of myelination; and thyroid hormone metabolic process. Located in extracellular space. Is expressed in thyroid gland; thyroid gland follicle; thyroid gland left lobe colloid-filled follicles; thyroid gland lobe; and thyroid gland right lobe colloid-filled follicles. Used to study congenital hypothyroidism. Human ortholog(s) of this gene implicated in Graves' disease; autoimmune thyroiditis; goiter; and thyroid dyshormonogenesis 3. Orthologous to human TG (thyroglobulin). [provided by Alliance of Genome Resources, Apr 2022]

Tg 基因产物(1)

mRNA Protein Name
NM_009375.2 NP_033401.2 thyroglobulin precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IDA
IDA: 通过直接分析推断
19276074 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within iodide transport IMP
IMP: 通过突变表型推断
3803305 MGI
acts upstream of or within regulation of myelination IMP
IMP: 通过突变表型推断
1508304 MGI
involved in thyroid hormone generation IDA
IDA: 通过直接分析推断
12782676 MGI
acts upstream of or within thyroid hormone metabolic process IMP
IMP: 通过突变表型推断
3803305 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
12782676 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

thyroglobulin

congenital goiter

相关产品

Approval
生物活性分子 (5)
目录号 产品名 作用方式
纯度 是否罕见病
HY-10409 Fedratinib 99.87% 是
HY-10409A Fedratinib hydrochloride hydrate 99.92% 是
HY-B0747 Eicosapentaenoic acid ethyl ester 98.0% 否
HY-111023 Nemonoxacin malate Inhibitor 99.29% 否
HY-165090 1,3-Distearoyl-2-lauroyl glycerol / 否
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P99538 Ublituximab Inhibitor 98.42% 否
Clinical Phase
生物活性分子 (14)
目录号 产品名 作用方式
纯度 Phase
HY-165051 1,3-Dibutyryl-2-oleoyl glycerol / Phase 4
HY-165037 1,2-Dimyristoyl-3-eicosapentaenoyl-rac-glycerol / Phase 3
HY-19359 Vilagletistat Inhibitor 99.97% Phase 2
HY-10111 TG100-115 Inhibitor 99.41% Phase 2
HY-19867A Burixafor hydrobromide Antagonist 98.0% Phase 2
HY-10186 TG 100801 Inhibitor 98.61% Phase 2
HY-15163 Zotiraciclib Inhibitor 99.88% Phase 2
HY-14783 Apricoxib Inhibitor 98.84% Phase 2
HY-145522 13-Dimyristoyl-2-Eicosapentaenoyl Glycerol / Phase 2
HY-19867 Burixafor Antagonist / Phase 2
HY-10187 TG 100801 Hydrochloride Inhibitor / Phase 2
HY-P2962 Transglutaminase, Streptoverticillium mobaraense / Phase 1
HY-137438 Edralbrutinib Inhibitor 99.75% Phase 1
HY-123765 JTT-553 Inhibitor / Phase 1
抗体抑制剂 (3)
目录号 产品名 作用方式
纯度 Phase
HY-P99833 Cosibelimab Inhibitor 99.90% Phase 3
HY-P99512 Zampilimab Inhibitor ≥99.0% Phase 2
HY-P990694 Zeripatamig Inhibitor ≥99.0% Phase 1
Pre-clinical Phase
生物活性分子 (209)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-112540B Acetoacetic acid sodium / 否
HY-15338 TG003 Inhibitor 99.57% 否
HY-112540A Acetoacetic acid lithium 98.0% 否
HY-153523 Hi 76-0079 Inhibitor 99.90% 否
HY-N2118 Bilobetin Activator 99.71% 否
HY-15166 (E/Z)-Zotiraciclib Inhibitor 99.96% 否
HY-18971 TG4-155 Antagonist 99.91% 否
HY-112540 Acetoacetic acid 95.0% 否
HY-117678 TG-2-IN-1 Inhibitor 98.0% 否
HY-10410 TG101209 98.81% 否
HY-W076543 5-(Biotinamido)pentylamine 99.96% 否
HY-16978 TG6-10-1 Antagonist 99.50% 否
HY-110381 JNJ-DGAT2-A Inhibitor 98.26% 否
HY-123290 KCC009 Inhibitor 98.06% 否
HY-156010 PPARγ-IN-2 Inhibitor 99.57% 否
HY-15166A (E/Z)-Zotiraciclib hydrochloride Inhibitor 99.90% 否
HY-N2078 Yamogenin 99.86% 否
HY-10185 TG 100572 Hydrochloride Inhibitor 98.76% 否
HY-146726S Tripentadecanoin-d29 99.24% 否
HY-B1434 7-Aminocephalosporanic acid Inhibitor 98.0% 否
HY-139362 Enpp-1-IN-2 Inhibitor 99.51% 否
HY-129126 NC9 Inhibitor 99.98% 否
HY-145933 BJJF078 Inhibitor 99.34% 否
HY-15166B (E/Z)-Zotiraciclib citrate Inhibitor 99.83% 否
HY-158774 TG2-179-1 Inducer 99.67% 否
HY-164049 TG8-260 Antagonist 99.13% 否
HY-W015600 2-Acetamidophenol 99.61% 否
HY-114994 MS437 Activator 98.0% 否
HY-172089 TG101209 analog 1 Inducer 98.27% 否
HY-N0368R Linalool (Standard) 97.16% 否
HY-128595 MT-4 Inhibitor 99.84% 否
HY-122709 TG2 inhibitor VA4 Inhibitor 99.66% 否
HY-W012802 Methyl 1H-pyrrole-2-carboxylate 99.98% 否
HY-W674124 Tripentadecanoin 98.0% 否
HY-14956 Nemonoxacin Inhibitor 99.77% 否
HY-13514 TG 100713 Inhibitor 99.21% 否
HY-N0368S Linalool-d3 95.17% 否
HY-122631 TG693 99.95% 否
HY-146914S 16:0-18:0-16:0 TG-d5 99.90% 否
HY-155102 PROTAC TG2 degrader-2 Degrader 99.15% 否
HY-14956S Nemonoxacin-d3 Inhibitor 99.93% 否
HY-161939 7030B-C5 Inhibitor 99.78% 否
HY-162141 MD102 / 否
HY-177133 Suvigletistat Inhibitor 99.82% 否
HY-23199 H2-003 Inhibitor 99.53% 否
HY-P11178 Corisin Inducer 99.45% 否
HY-P1822 BDC2.5 mimotope 1040-31 Agonist 99.75% 否
HY-W015600S 2-Acetamidophenol-d3 99.48% 否
HY-165041 1,3-Dioleoyl-2-stearoyl glycerol 99.9% 否
HY-W704600 1,3-Distearoyl-2-oleoyl glycerol 98.10% 否
HY-102073 TG53 Inhibitor 98.6% 否
HY-146913S 15:0-18:1-15:0 TG-d5 / 否
HY-146917S 20:0-20:1-20:0 TG-d5 99.90% 否
HY-15338A (E/Z)-TG003 Inhibitor / 否
HY-158614 1-Palmitoyl-2-12-PAHSA-3-oleoyl-sn-glycerol 99.9% 否
HY-158763A MPI8 TFA Inhibitor / 否
HY-163164S 18:1-17:1-18:1 TG-d5 99.00% 否
HY-165054 1-Palmitoyl-2-stearoyl-3-oleoyl-rac-glycerol 99.9% 否
HY-E70575 Endonuclease VIII / 否
HY-10184 TG 100572 Inhibitor / 否
HY-146799S 15:0-18:1-15:0 TG-d7 99.0% 否
HY-160132 TG-2-IN-4 Inhibitor 99.62% 否
HY-163163S 18:1-21:2-18:1 TG-d5 99.00% 否
HY-165091 1,2-Dioctanoyl-3-decanoyl-rac-glycerol 99.0% 否
HY-172083 15:0-18:1-15:0 TG 99.0% 否
HY-N11286 Tridocosahexaenoylglycerol 98.7% 否
HY-N7953 1,2-Dioleoyl-3-linoleoyl-rac-glycerol 95.0% 否
HY-W587772 Mono(2-ethyl-5-hydroxyhexyl) terephthalate 98.27% 否
HY-10104 GRL-8234 Inhibitor / 否
HY-103537A BIIB042 Modulator / 否
HY-10409S Fedratinib-d9 / 否
HY-111298 TG 41 Modulator / 否
HY-115705S 1,2,3-Tri-10(Z)-Heptadecenoyl Glycerol-d5 / 否
HY-116845 TG3-95-1 / 否
HY-118243 KMS88009 Inhibitor / 否
HY-119316 CM-414 Inhibitor / 否
HY-125958 AA9 Inhibitor / 否
HY-146398 AMPK activator 6 Activator / 否
HY-146737S Tripentadecanoin-d5 / 否
HY-146912S 14:0-16:1-14:0 TG-d5 / 否
HY-146916S 19:0-12:0-19:0 TG-d5 99.0% 否
HY-149257 HAT-SIL-TG-1&AT Inhibitor / 否
HY-14956S1 Nemonoxacin-d3-1 Inhibitor / 否
HY-14956S2 Nemonoxacin-d4 Inhibitor / 否
HY-151997S 1,2-Dioleoyl-3-lauroyl-rac-glycerol-13C3 / 否
HY-155643 PROTAC TG2 degrader-1 Inhibitor / 否
HY-157254 AA10 Inhibitor / 否
HY-157975 LM11 Inhibitor / 否
HY-158659 TG11-77 hydrochloride Antagonist / 否
HY-161985 PPARγ-IN-3 Inhibitor / 否
HY-163165S 16:0-19:2-16:0 TG-d5 / 否
HY-163345 5-HT7R antagonist 2 Antagonist / 否
HY-165038 1,2-Didecanoyl-3-stearoyl-rac-glycerol / 否
HY-165039 1,3-Dioleoyl-2-octanoyl glycerol / 否
HY-165046 1,2,3-Trilinoelaidoyl glycerol Inhibitor / 否
HY-165049 1-Stearoyl-2-oleoyl-3-linoleoyl-rac-glycerol Substrate / 否
HY-165053 1,3-Distearoyl-2-palmitoyl glycerol / 否
HY-165089 1,2-Dioleoyl-3-lauroyl-rac-glycerol / 否
HY-165094 1-Myristoyl-2-linoleoyl-3-palmitoyl-rac-glycerol / 否
HY-165106 1,2-Dibutyryl-3-palmitoyl-rac-glycerol / 否
HY-165108 1,2-Dilinoleoyl-3-α-linolenoyl-rac-glycerol / 否
HY-165109 1,3-Dioleoyl-2-lauroyl glycerol / 否
HY-165110 1-Stearoyl-2-palmitoyl-3-oleoyl-rac-glycerol / 否
HY-165111 1,2-Dioleoyl-3-myristoyl-rac-glycerol / 否
HY-165112 1,2-Dioleoyl-3-α-linolenoyl-rac-glycerol / 否
HY-165113 1,2-Distearoyl-3-arachidoyl-rac-glycerol / 否
HY-173545 1-Palmitoyl-2-10-oahsa-3-oleoyl-sn-glycerol / 否
HY-173546 1-Palmitoyl-2-12-oahsa-3-oleoyl-sn-glycerol / 否
HY-173547 1-Palmitoyl-2-9-pahsa-3-oleoyl-sn-glycerol / 否
HY-173548 1-Palmitoyl-2-10-pahsa-3-oleoyl-sn-glycerol / 否
HY-176271 MAO-B-IN-45 / 否
HY-176751 TG-2-IN-5 Inhibitor / 否
HY-176817 GPR109 receptor agonist-3 Agonist / 否
HY-176981 TG (18:2_20:3_20:4) / 否
HY-176982 TG (16:0_16:1_20:4) / 否
HY-176983 TG (16:0_18:2_20:4) / 否
HY-176984 TG (18:0_18:2_20:4) / 否
HY-176985 TG (18:1_20:2_20:4) / 否
HY-176986 TG (16:0_18:1_20:4) / 否
HY-176987 TG (18:0_18:1_20:4) / 否
HY-176988 TG (18:0_20:1_20:4) / 否
HY-176989 TG (16:0_16:0_20:4) / 否
HY-178015 THR-β agonist 11 Agonist / 否
HY-180322 TG2-IN-3h Inhibitor / 否
HY-181634S 16:0-15:1-16:0 TG-d5 / 否
HY-181709 TPM003 Agonist / 否
HY-181732 PROTAC TG2 Degrader-3 / 否
HY-181737 E3 Ligase Ligand-linker Conjugate 225 / 否
HY-182325 DB-310 Inhibitor / 否
HY-182544S 14:0-13:0-14:0 TG-d5 / 否
HY-182545S 14:0-15:1-14:0 TG-d5 / 否
HY-182554S 14:0-17:1-14:0 TG-d5 / 否
HY-182556S 16:0-17:1-16:0 TG-d5 / 否
HY-18970 TG6-129 Antagonist / 否
HY-D1545 Violamine R / 否
HY-E70436 Human keratinocyte transglutaminase / 否
HY-E70437 Guinea pig liver transglutaminase / 否
HY-E70439 Human epidermal transglutaminase / 否
HY-E70453 Human prostate transglutaminase / 否
HY-E70454 Human neuronal transglutaminase / 否
HY-N11551 Salvifaricin / 否
HY-N12249 7-Deoxy-trans-dihydronarciclasine Inhibitor / 否
HY-N15859 16:0-LR/18:1/18:1 TG - Lissamine rhodamine / 否
HY-N15874 C16/C11-TF/C12-DNP TG / 否
HY-N15875 18:1-18:1-C11 BODIPY 505/515 TG / 否
HY-N15876 18:1-6:0 DNP-C11 BODIPY 505/515 TG / 否
HY-N15883 18:1-C11 BODIPY 505/515-C11 BODIPY 505/515 TG / 否
HY-N7907 Myricetin-3-O-β-D-xylopyranosyl-(1→2)-β-D-glucopyranoside / 否
HY-N8214 Isorhamnetin 3-O-β-D-glucose-7-O-β-D-gentiobioside / 否
HY-P10677 HB-3-20 Degrader / 否
HY-P11348 TG-MMP-Lys Substrate / 否
HY-P11349 TG-Gln / 否
HY-P1822A BDC2.5 mimotope 1040-31 TFA Inhibitor / 否
HY-RS14432 TG Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W423707 TG 100948 Inhibitor / 否
HY-115705 1,2,3-Tri-10(Z)-heptadecenoyl glycerol / 否
HY-117110 Arginylproline / 否
HY-122989 Aristolactam BIII Inhibitor / 否
HY-125830 ITIC / 否
HY-142971 1-Myristoyl-2-Linoleoyl-3-Oleoyl-rac-glycerol / 否
HY-142974 1,2-Dioleoyl-3-Docosohexaenoyl-rac-glycerol / 否
HY-146915S 17:0-17:1-17:0 TG-d5 99.90% 否
HY-158749 1-Oleoyl-2-lauroyl-3-palmitoyl-rac-glycerol / 否
HY-158763 MPI8 Inhibitor / 否
HY-158945 1,3-Dipalmitoleoyl-2-11(Z)-octadecenoyl glycerol / 否
HY-158946 1,2-Dielaidoyl-3-linoleoyl-rac-glycerol / 否
HY-158948 1-Palmitoyl-2-11(Z)-octadecenoyl-3-butyroyl-rac-glycerol / 否
HY-158949 1-Palmitoyl-2-11(Z)-octadecenoyl-3-oleoyl-rac-glycerol / 否
HY-158957 1,3-Diheptadecanoyl-2-oleoyl glycerol / 否
HY-158959 1,3-Diarachidonoyl-2-oleoyl glycerol / 否
HY-158960 1,2-Dioleoyl-3-arachidonoyl-rac-glycerol / 否
HY-158961 1,3-Dielaidoyl-2-oleoyl glycerol / 否
HY-158963 1,3-Dipalmitoyl-2-octanoyl glycerol / 否
HY-158964 1-Palmitoyl-2-oleoyl-3-linolenoyl-rac-glycerol / 否
HY-160984 Rotraxate / 否
HY-16266 JNJ-DGAT1-A Inhibitor / 否
HY-163166S 18:1-19:2-18:1 TG-d5 / 否
HY-165036 1,2-Dieicosapentaenoyl-3-palmitoyl-rac-glycerol / 否
HY-165042 1,2-Dipalmitoyl-3-decanoyl-rac-glycerol / 否
HY-165047 1-Palmitoyl-2-linoleoyl-3-stearoyl-rac-glycerol / 否
HY-165048 1,3-Distearoyl-2-linoleoyl glycerol / 否
HY-165050 1,3-Dilinoleoyl-2-stearoyl glycerol / 否
HY-165052 1,3-Didocosahexaenoyl-2-palmitoyl glycerol / 否
HY-165055 1-Oleoyl-2-palmitoyl-3-linoleoyl-rac-glycerol / 否
HY-165056 1,2-Dipalmitoyl-3-linoleoyl-rac-glycerol / 否
HY-165092 1-Arachidoyl-2-palmitoyl-3-oleoyl-rac-glycerol / 否
HY-165093 1-Arachidoyl-2-oleoyl-3-palmitoyl-rac-glycerol / 否
HY-165095 1,2-Dipalmitoleoyl-3-palmitoyl-rac-glycerol / 否
HY-165105 1,3-Dioleoyl-2-decanoyl glycerol / 否
HY-165107 1,2-Dioctanoyl-3-stearoyl-rac-glycerol / 否
HY-165115 1,2-Dipalmitoyl-3-pentadecanoyl-rac-glycerol / 否
HY-165426 HB-230 / 否
HY-169473 1,2,3-Tri-13(E)-docosenoyl glycerol 99.9% 否
HY-170465 1,2-Distearoyl-3-butyryl-glycerol / 否
HY-170469 1,2-Dioleoyl-3-caprin / 否
HY-171217 TG-100435 Inhibitor / 否
HY-173148 TKB272 Inhibitor / 否
HY-175648 Antiparasitic agent-28 Inhibitor / 否
HY-175725 NR4A1 agonist 1 Agonist / 否
HY-18112 AZ-4217 Inhibitor / 否
HY-N8353 Stachybotramide / 否
HY-RS16550 Tg Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21232 Cacna1a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22983 Tg Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-W010667 (Z)-2-(Oleoyloxy)propane-1,3-diyl dipalmitate / 否
HY-W643167 1,2,3-Tritridecanoylglycerol 99.97% 否
HY-W710440 1,2-Distearoyl-3-palmitoyl-rac-glycerol / 否
HY-W710512 Propane-1,2,3-triyl tritricosanoate-d5 / 否
HY-W923355 1,2,3-Trieicosapentaenoyl glycerol / 否
抗体抑制剂 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991904 TG20 Inhibitor / 否
HY-P991947 ELB041 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tg NCBI NCBI:7038
Canis familiaris Tg NCBI NCBI:482047
Macaca fascicularis Tg NCBI NCBI:102121703
Susscrofa domestica Tg NCBI
Rattus norvegicus Tg NCBI NCBI:24826
Macaca mulatta Tg NCBI NCBI:701756
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