1. Gene
  2. Npff - neuropeptide FF-amide peptide precursor Gene

Npff - neuropeptide FF-amide peptide precursor Gene

种属: Rattus norvegicus

基因 ID: 60337 | 基因类型: protein coding

关于 Npff

功能概要

Enables G protein-coupled receptor binding activity and neuropeptide hormone activity. Involved in several processes, including ion homeostasis; negative regulation of Insulin secretion; and peptide hormone secretion. Located in several cellular components, including axon terminus; dendrite; and perikaryon. Orthologous to human NPFF (neuropeptide FF-amide peptide precursor). [provided by Alliance of Genome Resources, Apr 2022]

Npff 基因产物(1)

mRNA Protein Name
NM_022586.1 NP_072108.1 pro-FMRFamide-related neuropeptide FF preproprotein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor binding IDA
IDA: 通过直接分析推断
11024015 RGD
enables neuropeptide hormone activity IDA
IDA: 通过直接分析推断
11984823 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acute inflammatory response to antigenic stimulus IEP
IEP: 通过表达模式推断
15207282 RGD
involved in excitatory postsynaptic potential IDA
IDA: 通过直接分析推断
10938301 RGD
involved in maternal process involved in female pregnancy IEP
IEP: 通过表达模式推断
12619141 RGD
involved in negative regulation of appetite IDA
IDA: 通过直接分析推断
8801545 RGD
involved in negative regulation of heart rate IDA
IDA: 通过直接分析推断
8680863 RGD
involved in negative regulation of insulin secretion IDA
IDA: 通过直接分析推断
1704109 RGD
involved in positive regulation of blood pressure IDA
IDA: 通过直接分析推断
8680863 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
11024015 RGD
involved in regulation of membrane depolarization IDA
IDA: 通过直接分析推断
17289819 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
16529722 RGD
involved in somatostatin secretion IDA
IDA: 通过直接分析推断
1704109 RGD
involved in spinal cord development IEP
IEP: 通过表达模式推断
12619141 RGD
involved in vasopressin secretion IDA
IDA: 通过直接分析推断
8612481 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon terminus IDA
IDA: 通过直接分析推断
1924889 RGD
located in dendrite IDA
IDA: 通过直接分析推断
1924889 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
7891084 RGD
is active in neuronal dense core vesicle IDA
IDA: 通过直接分析推断
1924889 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
1924889 RGD
located in vesicle IDA
IDA: 通过直接分析推断
1924889 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

pro-FMRFamide-related neuropeptide FF

FMRFamide-related peptides

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Npff NCBI NCBI:8620