2. Academic Validation
  3. A novel phenanthrenolide and C-benzyl dihydrochalcones from Uvaria puguensis

A novel phenanthrenolide and C-benzyl dihydrochalcones from Uvaria puguensis

  • Nat Prod Lett. 2002 Aug;16(4):267-72. doi: 10.1080/10575630290020604.
John J Makangara 1,  Stephan A Jonker,  Mayunga H H Nkunya
Affiliations

Affiliation

  • 1 Department of Chemistry, University of Dar es Salaam, Tanzania.
PMID: 12168763 DOI: 10.1080/10575630290020604
Abstract

Two new natural products, the phenanthrenoid puguenolide (6-hydroxy-3-methoxy-4-oxapyren-5-one) and isoangoletin were isolated from the stem bark of the newly described Uvaria species, U. puguensis D.M. Johnson, together with the sesquiterpene guaiol and the usual C-benzyldihydrochalcones previously found in the genus Uvaria, viz. uvaretin, diuvaretin, chamuvaritin and a mixture of triuvaretin and isotriuvaretin. Structural elucidation was achieved through a combination of spectroscopic methods.

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