2. (R,S)-MDMA

(R,S)-MDMA 是一种 5-HT2A、5-HT2B 和 5-HT2C 受体的部分激动剂。(R,S)-MDMA 属于精神活性物质。(R,S)-MDMA 具有抗抑郁的活性。(R,S)-MDMA 可用于创伤后应激障碍、抑郁症等精神疾病的研究。

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(R,S)-MDMA

(R,S)-MDMA Chemical Structure

CAS No. : 859811-50-0

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Other Forms of (R,S)-MDMA:

(R,S)-MDMA 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(R,S)-MDMA acts as a partial agonist of 5-HT2A, 5-HT2B and 5-HT2C receptors. (R,S)-MDMA belongs to psychoactive substances. (R,S)-MDMA exhibits antidepressant activity. (R,S)-MDMA can be used for research on mental disorders such as post-traumatic stress disorder and depression[1].

体外研究
(In Vitro)

(R,S)-MDMA (55 min) 在 HEK293T 细胞中作为 5-HT2A、5-HT2B 和 5-HT2C 受体的部分激动剂，其 EC50 值分别为 249 nM、52.2 nM 和 158 nM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(R,S)-MDMA 相关抗体:
体内研究
(In Vivo)

(R,S)-MDMA (7.5 mg/kg；腹腔注射；单次给药) 可增强 C57BL/6J 小鼠在三室社交互动实验中的社交性[1]。
(R,S)-MDMA (7.5 mg/kg；腹腔注射) 在训练期间给药时，会在 C57BL/6J 小鼠中诱导出显著的社交条件性位置偏爱[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C57BL/6J mice (9-13 weeks old)[1]
Dosage: 7.5 mg/kg
Administration: i.p.; single dose
Result: Increased social interaction compared to vehicle controls over the 25-min exploration period.
Showed the largest difference in prosocial behavior compared to vehicle during the final 10 min of the 30-min assay.
分子量

192.25

Formula

C12H16O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(R,S)-MDMA 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R,S)-MDMA859811-50-0HEK293T cellssocial conditioned place preference5-HT2B receptors3-chamber social interaction assayserotonin5-HT2C receptors5-HT2A receptorsC57BL/6J miceInhibitorinhibitorinhibit

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