2. Others Metabolic Enzyme/Protease
  3. Isotope-Labeled Compounds Herbicide Photosystem II
  4. Sarmentine-d8

Sarmentine-d8 是氘代的 Sarmentine (HY-W099725)。Sarmentine 是一种广谱触杀型除草剂及 PSII 抑制剂，对菠菜的 IC50 为 3.0 μM、Ki 为 1.5 μM，对野生型反枝苋的 IC50 为 1.72 μM，对三嗪类抗性反枝苋的 IC50 为 0.97 μM。Sarmentine 会竞争结合 PSII 上质体醌的 QB 结合位点，从而阻断光合电子传递。Sarmentine 可通过靶向早期脂肪酸合成过程，从而抑制拟南芥的烯酰-ACP 还原酶，IC50 为 18.3 μM。Sarmentine 可诱导不依赖光照的质膜完整性丧失及电解质渗漏。Sarmentine 还具有抗疟原虫、抗分枝杆菌、抗结核及抗血小板聚集活性。

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Sarmentine-d<sub>8</sub>

Sarmentine-d8 Chemical Structure

CAS No. : 1795136-21-8

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规格 价格 是否有货 数量
1 mg ￥2886
4 - 5 周
10 mg 询价 4 - 5 周
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Sarmentine-d8 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sarmentine-d8 is the deuterium labeled Sarmentine. Sarmentine is a broad-spectrum contact herbicide and PSII inhibitor, with an IC50 of 3.0 μM and a Ki of 1.5 μM against spinach, an IC50 of 1.72 μM against wild-type Amaranthus retroflexus, and an IC50 of 0.97 μM against triazine-resistant Amaranthus retroflexus. Sarmentine competitively binds to the QB binding site of plastoquinone on PSII, thereby blocking photosynthetic electron transport. Sarmentine inhibits enoyl-ACP reductase in Arabidopsis thaliana by targeting the early fatty acid synthesis process, with an IC50 of 18.3 μM. Sarmentine induces light-independent loss of plasma membrane integrity and electrolyte leakage. Sarmentine also exhibits antiplasmodial, antimycobacterial, antituberculous, and antiplatelet aggregation activities[1].

产品应用

1. 该化合物可作为示踪剂。
2. 该化合物可作为 NMR、GC-MS 或 LC-MS 分析中的内标品，用于定量分析。
体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Sarmentine-d8 相关抗体:
分子量

229.39

Formula

C14H15D8NO
CAS 号
非标记 CAS
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Sarmentine-d8 相关分类

  • 摩尔计算器

  • 稀释计算器

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Keywords:

Sarmentine-d81795136-21-8Isotope-Labeled CompoundsHerbicidePhotosystem IIInhibitorinhibitorinhibit

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目录号：
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