Flagellin from S. typhimurium 是一种有效的 TLR5 激动剂。Flagellin from S. typhimurium 可以激活免疫细胞,抑制黑色素瘤细胞的活性。Flagellin from S. typhimurium 激活细胞中依赖于 TLR5/MyD88/TRAF6 信号轴的 NF-κB 通路。Flagellin from S. typhimurium 可通过促进 IL-8 生成、抑制 IL-10 生成并提高 IFN-γ/IL-10 比值,在原代鸡肝细胞-非实质细胞共培养体系中诱导促炎反应。Flagellin from S. typhimurium 可用于黑色素瘤、炎症疾病的研究。
鸡肌腱蛋白,suitable for cell culture
Chicken Tenascin,suitable for cell culture 是一种糖蛋白,可形成二硫键连接的六聚体。Chicken Tenascin,suitable for cell culture 由重复的结构域组成,包括 EGF 样重复序列、纤连蛋白 III 型重复序列和与纤维蛋白原同源的区域。Chicken Tenascin,suitable for cell culture 可用于细胞培养。
司太立胺A
Stellettamide A TFA 是一种被发现存在于海洋海绵中的海洋毒素。Stellettamide A TFA 是一种钙调蛋白抑制剂。Stellettamide A TFA 可抑制 Ca2+/Mg2+ ATPase、磷酸二酯酶、肌球蛋白轻链以及 Mg2+-ATPase。Stellettamide A TFA 可抑制高 K+ 和 Ca2+ 诱导的通透化平滑肌收缩。Stellettamide A TFA 对 Mortierella remannianus 具有抗真菌活性。Stellettamide A TFA 可用于真菌感染的研究。
朝藿定C
Epmedin C (Epimedin-C; Baohuoside-VI) 是一种口服有效的抗炎剂和免疫调节剂,够靶向结合 UCP1、Caspase-1、CDK2 及 Keap1 等多种关键蛋白。Epmedin C 通过破坏 CDK2/Cyclin E 的复合物功能、抑制上皮细胞增殖。Epmedin C 同时上调 Nrf2 表达、降低活性氧水平并抑制促炎因子分泌,从而有效恢复抗体生成并缓解组织损伤。Epmedin C 具有良好的安全性,且无肝毒性或皮肤致敏性,Epmedin C 已用于肥胖症、Deoxynivalenol (HY-N6684) 诱导的免疫毒性以及乳腺增生等疾病研究。
Flagellin from S. typhimurium 是一种有效的 TLR5 激动剂。Flagellin from S. typhimurium 可以激活免疫细胞,抑制黑色素瘤细胞的活性。Flagellin from S. typhimurium 激活细胞中依赖于 TLR5/MyD88/TRAF6 信号轴的 NF-κB 通路。Flagellin from S. typhimurium 可通过促进 IL-8 生成、抑制 IL-10 生成并提高 IFN-γ/IL-10 比值,在原代鸡肝细胞-非实质细胞共培养体系中诱导促炎反应。Flagellin from S. typhimurium 可用于黑色素瘤、炎症疾病的研究。
鸡肌腱蛋白,suitable for cell culture
Chicken Tenascin,suitable for cell culture 是一种糖蛋白,可形成二硫键连接的六聚体。Chicken Tenascin,suitable for cell culture 由重复的结构域组成,包括 EGF 样重复序列、纤连蛋白 III 型重复序列和与纤维蛋白原同源的区域。Chicken Tenascin,suitable for cell culture 可用于细胞培养。
朝藿定C
Epmedin C (Epimedin-C; Baohuoside-VI) 是一种口服有效的抗炎剂和免疫调节剂,够靶向结合 UCP1、Caspase-1、CDK2 及 Keap1 等多种关键蛋白。Epmedin C 通过破坏 CDK2/Cyclin E 的复合物功能、抑制上皮细胞增殖。Epmedin C 同时上调 Nrf2 表达、降低活性氧水平并抑制促炎因子分泌,从而有效恢复抗体生成并缓解组织损伤。Epmedin C 具有良好的安全性,且无肝毒性或皮肤致敏性,Epmedin C 已用于肥胖症、Deoxynivalenol (HY-N6684) 诱导的免疫毒性以及乳腺增生等疾病研究。
司太立胺A
Stellettamide A TFA 是一种被发现存在于海洋海绵中的海洋毒素。Stellettamide A TFA 是一种钙调蛋白抑制剂。Stellettamide A TFA 可抑制 Ca2+/Mg2+ ATPase、磷酸二酯酶、肌球蛋白轻链以及 Mg2+-ATPase。Stellettamide A TFA 可抑制高 K+ 和 Ca2+ 诱导的通透化平滑肌收缩。Stellettamide A TFA 对 Mortierella remannianus 具有抗真菌活性。Stellettamide A TFA 可用于真菌感染的研究。
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
MedchemExpress Validation 03
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
MedchemExpress Validation 04
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.
MedchemExpress Validation
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred
to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was
used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.