2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. ERβ agonist-2

ERβ agonist-2 (Page 72) 是一种选择性的 ERβ 激动剂，EC50 为 800 nM 或更低。ERβ agonist-2 可选择性抑制 T 细胞的活化和/或增殖，从而降低受试者循环 T 细胞水平，而对循环中性粒细胞、单核细胞或B细胞水平无显著影响。ERβ agonist-2 可用于心肌梗死后的慢性心力衰竭，以及移植物抗宿主病、多发性硬化症和实验性自身免疫性脑脊髓炎研究。

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ERβ agonist-2

ERβ agonist-2 Chemical Structure

CAS No. : 628321-25-5

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ERβ agonist-2 相关抗体

Top Publications Citing Use of Products

查看 Estrogen Receptor/ERR 亚型特异性产品:

查看所有亚型
Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ERβ agonist-2 (Page 72) is a selective ERβ agonist with an EC50 of 800 nM or lower. ERβ agonist-2 selectively inhibits T cell activation and/or proliferation, thereby reducing circulating T cell levels in subjects, without exerting significant effects on circulating neutrophil, monocyte or B cell levels. ERβ agonist-2 is applicable to studies of chronic heart failure after myocardial infarction, as well as graft-versus-host disease, multiple sclerosis and experimental autoimmune encephalomyelitis[1].

IC50 & Target[1]

ERβ

800 or low nM (EC50)

体外研究
(In Vitro)

ERβ agonist-2 在雌激素受体 β (ERβ) 上的 EC50 为 800 nM 或更低[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

ERβ agonist-2 相关抗体:
分子量

304.34

Formula

C19H16N2O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ERβ agonist-2 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ERβ agonist-2628321-25-5ERβ agonist2ERβ agonist 2Estrogen Receptor/ERRgraft-versus-host diseaseCD4+ T-cellsB-cellestrogen receptor betaT-cellmonocyteneutrophilexperimental autoimmune encephalomyelitismultiple sclerosischronic heart failureInhibitorinhibitorinhibit

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